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Ibuprofenol

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Identification
Molecular formula
C12H18O
CAS number
26014-50-6
IUPAC name
2-(3-isopropylphenyl)propan-2-ol
State
State

At room temperature, Ibuprofenol exists in a solid state.

Melting point (Celsius)
79.00
Melting point (Kelvin)
352.00
Boiling point (Celsius)
253.00
Boiling point (Kelvin)
526.00
General information
Molecular weight
178.27g/mol
Molar mass
178.2710g/mol
Density
0.9605g/cm3
Appearence

Ibuprofenol presents as a white to off-white crystalline powder. It is important to note that the physical state may slightly differ based on purity and processing methods.

Comment on solubility

Solubility of 2-(3-isopropylphenyl)propan-2-ol

The solubility of 2-(3-isopropylphenyl)propan-2-ol can be characterized by several key factors that influence its behavior in various solvents.

Factors Affecting Solubility

  • Polarity: The compound contains a hydroxyl group (–OH), which imparts some degree of polarity, allowing it to engage in hydrogen bonding with water molecules.
  • Hydrophobic Character: The isopropyl group and the phenyl ring contribute a significant hydrophobic nature, which can limit its solubility in polar solvents.

As a result, the solubility of 2-(3-isopropylphenyl)propan-2-ol can be summarized as follows:

  • In Water: Its solubility is likely to be moderate due to the competing effects of the polar hydroxyl group and the hydrophobic aromatic structure.
  • In Organic Solvents: It shows better solubility in non-polar or less polar organic solvents, such as ethanol or acetone, where the hydrophobic interactions are favorable.

In conclusion, while 2-(3-isopropylphenyl)propan-2-ol has some solubility in water due to its polar functional group, its overall solubility profile favors non-polar environments significantly more. Understanding these solubility characteristics is crucial for applications and further scientific exploration.

Interesting facts

Interesting Facts about 2-(3-Isopropylphenyl)propan-2-ol

2-(3-Isopropylphenyl)propan-2-ol, commonly known in synthetic organic chemistry, is an intriguing compound with a variety of applications and properties. Here are some fascinating insights:

  • Origin and Structure: This compound features a unique structure characterized by a tertiary alcohol group and an isopropyl-substituted phenyl ring which grants it interesting reactivity and physical properties.
  • Reactivity: The presence of the hydroxyl group (-OH) means that 2-(3-isopropylphenyl)propan-2-ol is likely to participate in various important chemical reactions such as oxidation and esterification.
  • Synthetic Utility: Compounds like this are often employed as intermediates in the synthesis of pharmaceuticals and agrochemicals. Its unique molecular structure lends it variety in potential reactions within organic syntheses.
  • Chiral Nature: The carbon center to which the hydroxyl group is attached makes this compound a potential chiral molecule, leading to different configurations and potentially unique biological activities.
  • Biological Relevance: Some tertiary alcohols are known for their activity as solvents or pharmacological agents, and there is ongoing research into how structural modifications affect their therapeutic effects.

As a compound, 2-(3-isopropylphenyl)propan-2-ol exemplifies the intersection of structural chemistry and biological applications, making it a valuable subject of study for both chemists and those interested in pharmacodynamics.

Overall, this compound not only enriches the tapestry of organic chemistry but also offers promising avenues for scientific exploration and application.

Synonyms
14860-89-0
2-(3-ISOPROPYLPHENYL)PROPAN-2-OL
2-(3-propan-2-ylphenyl)propan-2-ol
2-(3-iso-Propylphenyl)-2-propanol
3-Isopropyl-alpha,alpha-dimethylbenzyl alcohol
2-[3-(propan-2-yl)phenyl]propan-2-ol
Benzenemethanol, alpha,alpha-dimethyl-3-(1-methylethyl)- (9CI)
m-Hydroxydiisopropylbenzene
m-Oxidiisopropylbenzene
BRN 2250517
alpha,alpha-Dimethyl-m-isopropylbenzyl alcohol
MFCD00046571
Benzenemethanol, alpha,alpha-dimethyl-3-(1-methylethyl)-
3-Isopropyl-|A,|A-dimethylbenzyl alcohol
BENZYL ALCOHOL, alpha,alpha-DIMETHYL-m-ISOPROPYL-
orb1986442
SCHEMBL3370465
SCHEMBL31095742
DTXSID40164034
m-isopropylphenyl dimethyl carbinol
AKOS037646145
AS-66881
CS-0273809
m-isopropyl-alpha,alpha-dimethylbenzyl alcohol
D93398
EN300-1846991