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Meloxicam

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Identification
Molecular formula
C14H13N3O4S2
CAS number
71125-38-7
IUPAC name
2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide
State
State

Meloxicam is typically a solid at room temperature.

Melting point (Celsius)
254.00
Melting point (Kelvin)
527.15
Boiling point (Celsius)
809.20
Boiling point (Kelvin)
1 082.35
General information
Molecular weight
351.40g/mol
Molar mass
351.4040g/mol
Density
1.4200g/cm3
Appearence

Meloxicam is a pale yellow powder that is practically insoluble in water. It has a crystalline solid structure.

Comment on solubility

Solubility of 2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide

The solubility of the compound C14H13N3O4S2, also known as 2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide, can present interesting characteristics worth noting. Generally, the solubility of organic compounds such as this one can be influenced by several factors:

  • Polarity: The presence of functional groups like sulfonamide and dioxo can increase polarity, which may enhance solubility in polar solvents.
  • Hydrogen Bonding: The sulfonamide group can participate in hydrogen bonding, potentially improving solubility in water and other protic solvents.
  • Molecular Structure: The thieno[3,2-e]thiazine core may affect spatial orientation, influencing how the compound interacts with solvent molecules.
  • Solvent Choice: Solubility can vary widely depending on the solvent; this compound may dissolve better in solvents like dimethyl sulfoxide (DMSO) or methanol compared to non-polar solvents.

In summary: The solubility of 2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide is likely to be appreciable in polar solvents due to its structural features, yet further experimental data would be essential to quantify its solubility under various conditions.

Interesting facts

Interesting Facts about 2-(3-methoxyphenyl)-1,1-dioxo-3,4-dihydrothieno[3,2-e]thiazine-6-sulfonamide

This fascinating compound, often referred to by its structural classification, belongs to the thieno-thiazine family, which is a critical structural motif in medicinal chemistry. Here are some engaging insights into its properties and significance:

  • Medicinal Relevance: Compounds in this class are studied for their potential therapeutic applications. Research suggests they may exhibit antimicrobial and anti-inflammatory properties, making them of great interest in drug discovery.
  • Synthetic Pathways: The synthesis of this compound can involve various techniques, including cyclization and functionalization of existing molecules to create the complex thiazine framework.
  • Structure-Activity Relationship (SAR): Understanding how structural variations affect biological activity is crucial. The presence of substituents like the methoxy group can significantly influence the overall reactivity and interaction with biological targets.
  • Chromophore Characteristics: This compound likely has intriguing UV-Vis absorption properties, allowing for analysis and monitoring in various applications.
  • Research Potential: Given the ongoing exploration of thieno-thiazine derivatives, this compound stands at the crossroads of pharmaceutical innovation, with potential developments in treating various diseases.

Overall, this compound not only exemplifies the complexity of organic synthesis but also highlights the interplay between molecular structure and biological function. In pursuit of better healthcare solutions, such compounds are invaluable tools for scientists.

Synonyms
AL7182
3,,4-dihydro-2-(3-methoxyphenyl)-2h-thieno-[3,2-e]-1,2-thiazine-6-sulfonamide-1,1-dioxide
1bnn
2-(3-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1??-thieno(3,2-e)(1,2)thiazine-6-sulfonamide
2-(3-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1??-thieno[3,2-e][1,2]thiazine-6-sulfonamide
SCHEMBL678649
CHEMBL331858
BDBM11935
AL-7182
DB02602
AL1
NS00069458
Q27093572
2-(3-methoxyphenyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
2-(3-methoxyphenyl)-1,1-dioxo-2H,3H,4H-1$l^{6},7,2-thieno[3,2-e][1,2]thiazine-6-sulfonamide