Skip to main content

Clemastine Fumarate

ADVERTISEMENT
Identification
Molecular formula
C21H26ClNO2
CAS number
81410-25-9
IUPAC name
2-(3-methyl-2-phenyl-morpholin-4-ium-4-yl)ethyl 2-phenylbutanoate;chloride
State
State
At room temperature, clemastine fumarate is typically in a solid state as a crystalline powder. It is stable under normal conditions.
Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
422.80
Boiling point (Kelvin)
695.95
General information
Molecular weight
427.41g/mol
Molar mass
427.4130g/mol
Density
1.1600g/cm3
Appearence

The compound typically appears as a white or off-white solid in its salt form. It is usually found as a crystalline powder.

Comment on solubility

Solubility of 2-(3-methyl-2-phenyl-morpholin-4-ium-4-yl)ethyl 2-phenylbutanoate;chloride

The solubility of this compound is influenced by its complex structure and the presence of various functional groups. The salt form, being a chloride, plays a significant role in its solubility in different solvents. Here are some key points regarding its solubility:

  • Water Solubility: Due to the presence of the quaternary ammonium salt group, it is likely to have moderate solubility in water, facilitating interaction with biological systems.
  • Organic Solvents: The aromatic and aliphatic groups may improve solubility in organic solvents, particularly those that are polar, such as ethanol and methanol.
  • pH Dependence: The solubility of quaternary ammonium compounds can vary with pH, typically increasing in more acidic conditions.
  • Temperature Effects: Like many organic compounds, solubility may increase with temperature, allowing for greater dissolution in heated solvents.

This compound exemplifies the complex interplay of structure and solubility. As stated, "the overall solubility behavior can be significantly influenced by environmental conditions and the chemical structure of the compound." Understanding these factors is crucial for its practical applications, particularly in pharmaceutical and biochemical contexts.

Interesting facts

Interesting Facts about 2-(3-methyl-2-phenyl-morpholin-4-ium-4-yl)ethyl 2-phenylbutanoate; chloride

This compound is a fascinating example of a synthetic organic molecule that showcases the interplay between various functional groups and molecular structures. Comprising a morpholine ring, which is notable for its presence in numerous pharmacologically active compounds, this molecule has a range of intriguing properties.

Key Features and Applications:

  • Versatile Structure: The morpholine moiety contributes to the compound's biological activities, making it a point of interest in medicinal chemistry.
  • Pharmacological Potential: Its design suggests potential applications in drug development, possibly targeting a variety of biological pathways.
  • Chloride Ion: The presence of chloride indicates that this compound can participate in ionic interactions, which can enhance solubility and bioavailability.
  • Functional Groups: The ester functional group in the butanoate structure can influence the reactivity and stability of the compound, broadening its synthetic accessibility.

It is often said that "the right molecular architecture can lead to groundbreaking discoveries." In this case, this compound could potentially lead to novel therapeutic agents or materials used in various scientific research fields.

Furthermore, structure-activity relationship (SAR) studies can be performed with this compound, allowing scientists to optimize its efficacy and reduce any potential side effects that may arise from its structure.

As research continues into the myriad uses of such compounds, it remains pivotal for chemists to explore and understand their underlying mechanisms, paving the way for innovations that could significantly impact fields such as pharmacology, materials science, and beyond.

Synonyms
Fenbutrazate hydrochloride
Phenbutrazate hydrochloride
Fenbutrazate HCl
EINECS 229-330-5
UNII-8G5106B4AP
R 381
6474-85-7
2-(3-Methyl-2-phenylmorpholino)ethyl 2-phenylbutyrate hydrochloride
8G5106B4AP
2-Phenylbutyric acid 2-(3-methyl-2-phenylmorpholino)ethyl ester hydrochloride
4-Morpholineethanol, 3-methyl-2-phenyl-, 2-phenylbutyrate (ester) hydrochloride
alpha-Ethylbenzeneacetic acid 2-(3-methyl-2-phenyl-4-morpholinyl)ethyl ester hydrochloride
Phenyl-aethyl-essigsaeure-(phenyl-methyl)-morpholino-N-aethanolester-hydrochlorid [German]
Phenyl-aethyl-essigsaeure-(phenyl-methyl)-morpholino-N-aethanolester-hydrochlorid
Benzeneacetic acid, alpha-ethyl-, 2-(3-methyl-2-phenyl-4-morpholinyl)ethyl ester, hydrochloride
Butyric acid, 2-phenyl-, 2-(3-methyl-2-phenylmorpholino)ethyl ester, hydrochloride
FENBUTRAZATE HYDROCHLORIDE [MI]
FENBUTRAZATE HYDROCHLORIDE (MART.)
FENBUTRAZATE HYDROCHLORIDE [MART.]
FENBUTRAZATE HYDROCHLORIDE [WHO-DD]
R-381
BENZENEACETIC ACID, .ALPHA.-ETHYL-, 2-(3-METHYL-2-PHENYL-4-MORPHOLINYL)ETHYL ESTER, HYDROCHLORIDE (1:1)
229-330-5
BENZENEACETIC ACID, ALPHA-ETHYL-, 2-(3-METHYL-2-PHENYL-4-MORPHOLINYL)ETHYL ESTER, HYDROCHLORIDE (1:1)
Q27270389