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2-(3-methyl-4-propoxyphenyl)ethanehydroxamic acid

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Identification
Molecular formula
C13H19NO3
CAS number
161625-98-3
IUPAC name
2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid
State
State

This compound is generally found in a solid state at room temperature. It exists as a stable crystalline powder under standard conditions.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
312.00
Boiling point (Kelvin)
585.15
General information
Molecular weight
223.30g/mol
Molar mass
223.2870g/mol
Density
1.1800g/cm3
Appearence

2-(3-methyl-4-propoxyphenyl)ethanehydroxamic acid appears as a white to off-white crystalline powder. The compound is typically odorless and is not readily soluble in water, but may dissolve in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

Comment on solubility

Solubility of 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid

Understanding the solubility of 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid is vital for its practical applications and effectiveness in various formulations. The solubility of this compound can be influenced by several factors:

  • Polarity: This compound contains both hydrophobic (propoxy group) and hydrophilic (hydroxamic acid group) portions, which can create unique solubility characteristics in different solvents.
  • Temperature: As with many organic compounds, increased temperature generally enhances solubility. Conducting solubility tests at elevated temperatures may yield different solubility profiles.
  • pH Influence: The presence of the hydroxamic acid group suggests that its solubility could be pH-dependent, potentially becoming more soluble in basic conditions due to deprotonation.
  • Solvent Choice: Typically, this compound may show better solubility in organic solvents like ethanol or DMSO compared to water, reflecting the importance of solvent selection in solubility assessments.

In summary, the solubility of 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid appears to be multifaceted and affected by both intrinsic properties and environmental conditions. Therefore, it is essential to conduct careful experiments to fully understand its solubility behavior.

Interesting facts

Exploring 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid

2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid is a fascinating compound that belongs to the class of hydroxamic acids. Hydroxamic acids, in general, have significant biological importance and are well-acknowledged for their role as metal chelators in biochemical pathways. Here are some engaging aspects of this compound:

  • Biochemical Applications: Hydroxamic acids are known to interfere with metalloproteins and can modulate various enzymatic activities. This specific compound may demonstrate potential applications in fields such as drug development or agricultural chemistry.
  • Structure and Function: The presence of a hydroxamic acid functional group allows this compound to form complexes with transition metals, enhancing its reactivity and interaction in biological systems.
  • Medicinal Chemistry: Compounds like 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid can serve as templates for designing new pharmaceuticals, providing insight into structure-activity relationships (SAR).
  • Benefits in Research: Scientists often utilize derivatives of hydroxamic acids to study enzyme function and develop therapeutic agents for diseases where metal ions play a critical role.

Researchers are constantly exploring the capabilities of hydroxamic acids to broaden the horizons of medicinal chemistry. As one prominent chemist once said, "The beauty of chemistry lies in its ability to reveal the unseen connections that bind the materials of our world." This compound exemplifies such connections, merging organic chemistry with potential real-world applications.

As the field of chemistry evolves, compounds like 2-(3-methyl-4-propoxy-phenyl)ethanehydroxamic acid will continue to be of interest not only for their structural properties but also for their implications in advancing science and technology.

Synonyms
2-(4-Propoxy-m-tolyl)acetohydroxamic acid
ACETOHYDROXAMIC ACID, 2-(4-PROPOXY-m-TOLYL)-
23142-39-4
DTXSID70177718
RefChem:316791
DTXCID30100209