Skip to main content

2-(3-nitroanilino)acetic acid

ADVERTISEMENT
Identification
Molecular formula
C8H8N2O4
CAS number
55342-67-9
IUPAC name
2-(3-nitroanilino)acetic acid
State
State

At room temperature, 2-(3-nitroanilino)acetic acid exists as a solid. It is usually handled in its powder or crystalline form in laboratory settings.

Melting point (Celsius)
132.50
Melting point (Kelvin)
405.65
Boiling point (Celsius)
255.00
Boiling point (Kelvin)
528.15
General information
Molecular weight
212.19g/mol
Molar mass
212.1880g/mol
Density
1.4360g/cm3
Appearence

2-(3-nitroanilino)acetic acid typically appears as a crystalline solid that can vary in color from light yellow to brown, depending on purity and specific synthesis methods. The compound is known for its relatively high melting point and solubility in polar solvents such as water and alcohols.

Comment on solubility

Solubility of 2-(3-nitroanilino)acetic acid

The solubility of 2-(3-nitroanilino)acetic acid can be influenced by several factors, primarily its molecular structure and the nature of its functional groups. This compound, containing both an amine and a carboxylic acid group, suggests that it may exhibit interesting solubility characteristics in various solvents.

Solubility Characteristics:

  • Polar Solvents: Generally, compounds with carboxylic acid groups show good solubility in polar solvents such as water due to the ability to form hydrogen bonds.
  • Non-Polar Solvents: The presence of the aromatic nitro group may decrease solubility in non-polar solvents, as the interactions between the compound and non-polar solvent molecules are weaker.
  • pH Dependency: As this compound is an acid, its solubility can vary with pH. At lower pH levels, the acid group is protonated, potentially enhancing solubility, whereas at higher pH levels it may dissociate, further affecting its solubility behavior.

In summary, the solubility of 2-(3-nitroanilino)acetic acid is likely to be higher in polar solvents, particularly under conditions that favor the ionization of the carboxylic acid group. Understanding the specific solubility profile of this compound can be crucial for its applications in chemical reactions or pharmaceuticals.

Interesting facts

Interesting Facts about 2-(3-Nitroanilino)acetic Acid

2-(3-Nitroanilino)acetic acid is a fascinating compound that exhibits a variety of chemical properties and potential applications. Derived from a combination of both an amino group and an acetic acid functional group, this compound presents a unique structure with numerous implications in the field of chemistry.

Key Features:

  • Biological Significance: This compound has garnered interest due to its potential use in pharmaceutical applications, particularly in the development of medicinal agents that could target various biological pathways.
  • Reactivity: The presence of nitro and amino groups in its structure grants it the ability to undergo a variety of chemical reactions, making it a versatile building block in organic synthesis.
  • Research Applications: It is often studied for its role in creating derivatives that can serve as precursors for more complex chemical entities, particularly in the synthesis of dyes and pigments.
  • Analytical Uses: The compound can be employed in different analytical chemistry techniques, including spectrophotometry, where its distinct absorption characteristics can be exploited for identification purposes.

As you study 2-(3-nitroanilino)acetic acid, consider the diverse array of reactions it can participate in and the potential for innovation in synthetic chemistries. Its multifunctionality serves as a reminder of the intricate connections between compound structure and reactivity, illustrating the fascinating world of organic chemistry. As one chemist famously remarked, "In the world of chemistry, every compound tells a story."

In summary, 2-(3-nitroanilino)acetic acid is not just another compound; it is a gateway to understanding more complex chemical behavior and potential transformations that highlight the beauty and complexity of chemistry.

Synonyms
GLYCINE, N-(m-NITROPHENYL)-
10242-06-5
N-(m-Nitrophenyl)glycine
Glycine, N-(3-nitrophenyl)-
NSC 154513
BRN 2808393
DTXSID40145065
0-12-00-00709 (Beilstein Handbook Reference)
DTXCID5067556
2-(3-nitroanilino)acetic acid
(3-nitroanilino)acetic acid
3-nitrophenylglycine
m-nitrophenylglycine
NSC154513
(3-Nitrophenyl)glycine
phenylglycine, m-nitro-
Oprea1_781329
SCHEMBL1797099
SCHEMBL6192945
YWWRLAPJIGCYRN-UHFFFAOYSA-N
NSC-154513
AE-562/33487053