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2-(3-nitrophenyl)acetic acid

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Identification
Molecular formula
C8H7NO4
CAS number
6946-83-2
IUPAC name
2-(3-nitrophenyl)acetic acid
State
State

At room temperature, 2-(3-nitrophenyl)acetic acid exists in a solid state. The compound is often utilized in the synthesis of pharmaceuticals and other organic compounds.

Melting point (Celsius)
142.00
Melting point (Kelvin)
415.15
Boiling point (Celsius)
372.20
Boiling point (Kelvin)
645.40
General information
Molecular weight
181.15g/mol
Molar mass
181.1550g/mol
Density
1.4633g/cm3
Appearence

2-(3-Nitrophenyl)acetic acid appears as a crystalline solid that is typically white to pale yellow in color. The compound is stable under standard conditions but should be stored in a cool, dry place to maintain its stability.

Comment on solubility

Solubility of 2-(3-Nitrophenyl)acetic Acid

2-(3-Nitrophenyl)acetic acid, with the chemical formula C9H9NO4, presents interesting solubility characteristics that can be influenced by several factors:

  • Polarity: Being a carboxylic acid, 2-(3-nitrophenyl)acetic acid is generally considered polar, which can enhance its solubility in polar solvents like water.
  • Temperature: Increased temperature often leads to higher solubility of organic compounds. This compound may dissolve more readily in warm solutions.
  • pH Dependence: The solubility might also vary with pH since the presence of hydrogen ions can protonate the carboxyl group, affecting the overall ionization and solubility in a solution.
  • Solvent Type: It tends to be more soluble in organic solvents such as alcohols and acetone due to compatible solvation mechanisms.

According to research, the solubility of 2-(3-nitrophenyl)acetic acid in water is moderate, allowing it to be useful for various pharmaceutical applications. However, in non-polar solvents, its solubility significantly decreases.

In summary, the solubility of 2-(3-nitrophenyl)acetic acid showcases the importance of understanding environmental conditions and chemical interactions in predicting how this compound behaves in different media.

Interesting facts

Interesting Facts about 2-(3-Nitrophenyl)acetic Acid

2-(3-Nitrophenyl)acetic acid, also known by its IUPAC name, is a chemical compound that combines the characteristics of both acetic acid and a nitrophenyl group. This compound is noteworthy for several reasons:

  • Applications in Synthesis: This compound is used in the synthesis of various pharmaceuticals and agrochemicals. Its structure makes it a valuable intermediate in the preparation of bioactive molecules.
  • Importance in Research: Due to the presence of the nitro group, it serves as a point of interest in medicinal chemistry and material science, where it’s studied for its potential therapeutic effects.
  • Acidity: The carboxylic acid functional group contributes to its acidic nature, influencing its reactivity and making it useful in acid-base chemistry. This characteristic makes it useful in various chemical reactions.
  • Environmental Impact: Compounds like 2-(3-nitrophenyl)acetic acid serve as important indicators in environmental chemistry, especially in soil and water studies, helping researchers understand pollutant behavior.
  • Biological Activity: Research suggests that derivatives of this compound can exhibit anti-inflammatory and analgesic properties, making it of interest in pharmacology.

Overall, 2-(3-nitrophenyl)acetic acid not only acts as a critical building block in chemical synthesis but also opens up avenues for advancements in environmental and biological sciences. As quoted by chemists, “Understanding the structure-function relationship in such compounds can lead us to groundbreaking discoveries.”

Synonyms
3-Nitrophenylacetic acid
1877-73-2
2-(3-NITROPHENYL)ACETIC ACID
Benzeneacetic acid, 3-nitro-
m-Nitrophenylacetic acid
3-Nitrobenzeneacetic acid
(m-Nitrophenyl)acetic acid
ACETIC ACID, (m-NITROPHENYL)-
CCRIS 2337
EINECS 217-512-7
NSC 93911
BRN 2050088
WUKHOVCMWXMOOA-UHFFFAOYSA-
DTXSID60172075
DTXCID6094566
Benzeneacetic acid, 3-nitro-(9CI)
217-512-7
inchi=1/c8h7no4/c10-8(11)5-6-2-1-3-7(4-6)9(12)13/h1-4h,5h2,(h,10,11)
(3-nitrophenyl)acetic acid
MFCD00007278
(3-Nitro-phenyl)-acetic acid
MNP
1ai5
m-Nitrophenyl acetic acid
(3-nitrophenyl)aceticacid
3-nitrophenyl acetic acid
3-nitro phenyl acetic acid
Acetic acid, m-nitrophenyl-
SCHEMBL296300
CHEMBL139020
2-(3-nitro-phenyl)acetic acid
3-Nitrophenylacetic acid, 99%
SCHEMBL14134783
acetic acid, 2-(3-nitrophenyl)-
NSC93911
CL8780
NSC-93911
STK450326
AKOS000112327
CS-W001143
DB08193
FN12534
GS-3303
PB15594
PD004657
SY005215
DB-044648
N0442
NS00026136
EN300-64075
Q27097419
Z285184614