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2-(3-phenylazetidin-1-yl)ethanol

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Identification
Molecular formula
C11H15NO
CAS number
60946-98-1
IUPAC name
2-(3-phenylazetidin-1-yl)ethanol
State
State

The compound is typically found as a liquid at room temperature, and appears as a clear or slightly colored liquid.

Melting point (Celsius)
-30.00
Melting point (Kelvin)
243.15
Boiling point (Celsius)
258.50
Boiling point (Kelvin)
531.65
General information
Molecular weight
177.24g/mol
Molar mass
177.2370g/mol
Density
1.0640g/cm3
Appearence

2-(3-phenylazetidin-1-yl)ethanol is typically a colorless to pale yellow liquid. It may be observed as a clear liquid under normal conditions.

Comment on solubility

Solubility of 2-(3-phenylazetidin-1-yl)ethanol

The solubility of 2-(3-phenylazetidin-1-yl)ethanol in various solvents can be characterized by several important factors:

  • Polarity: The presence of hydroxyl (-OH) groups typically enhances solubility in polar solvents, such as water. However, the phenyl group may introduce some non-polar character, influencing the overall solubility.
  • Hydrogen Bonding: The hydroxyl group allows for potential hydrogen bonding interactions with solvent molecules, which can significantly increase solubility in polar solvents.
  • Temperature: As with many organic compounds, solubility is often temperature-dependent. Generally, an increase in temperature may improve solubility in many solvents.
  • Solvent Types: This compound may exhibit different solubility patterns in various solvents:
    • High solubility: In alcohols and other protic solvents due to hydrogen bonding capability.
    • Moderate solubility: In less polar solvents like dichloromethane.
    • Low solubility: In non-polar solvents such as hexane.

In summary, while 2-(3-phenylazetidin-1-yl)ethanol is expected to show favorable solubility characteristics in polar solvents due to its functional groups, the presence of the aromatic phenyl group may affect its overall solubility in various environments. Understanding these interactions is crucial for practical applications.

Interesting facts

Interesting Facts about 2-(3-phenylazetidin-1-yl)ethanol

2-(3-phenylazetidin-1-yl)ethanol is a fascinating compound that attracts attention due to its unique structure and potential applications. Here are some highlights:

  • Pharmaceutical Relevance: The compound features an azetidine ring, which is often found in biologically active molecules. This structure suggests the potential for pharmaceutical applications, particularly in the development of new drugs.
  • Amine Properties: As a secondary amine, it can act as a nucleophile in various chemical reactions, making it valuable in synthetic organic chemistry.
  • Synthetic Versatility: Its distinct structure allows for modifications that can lead to the synthesis of a variety of derivatives, enhancing its utility in research and application.
  • Chemical Behavior: The presence of both an alcohol and an azetidine moiety influences its reactivity, making it an interesting target for studying reaction mechanisms in organic chemistry.
  • Structure-Activity Relationships: Researchers are currently investigating how the molecular structure affects biological activity, paving the way for tailored compounds that can better interact with biological targets.

In conclusion, 2-(3-phenylazetidin-1-yl)ethanol stands out as a compound of interest for both its structural characteristics and its implications in medicinal chemistry. As research continues, it may contribute significantly to new therapeutic strategies and insights in the field of chemistry.

Synonyms
1-AZETIDINEETHANOL, 3-PHENYL-
3-Phenyl-1-azetidineethanol
L 2245
BRN 1426293
7215-11-4
DTXSID10222478
DTXCID10144969
5-20-06-00284 (beilstein handbook reference)