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2-(3-Pyridyl)-1,3-benzoxazole

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Identification
Molecular formula
C12H8N2O
CAS number
30550-65-1
IUPAC name
2-(3-pyridyl)-1,3-benzoxazole
State
State

The compound is in a solid state at room temperature, typically existing as a crystalline solid or powder.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.20
Boiling point (Celsius)
289.50
Boiling point (Kelvin)
562.70
General information
Molecular weight
194.21g/mol
Molar mass
194.2080g/mol
Density
1.2507g/cm3
Appearence

2-(3-Pyridyl)-1,3-benzoxazole is typically found as a crystalline solid. The appearance of the compound may vary slightly depending on purity and form but usually manifests as white to off-white colored crystals or powder.

Comment on solubility

Solubility of 2-(3-pyridyl)-1,3-benzoxazole

The solubility of 2-(3-pyridyl)-1,3-benzoxazole in various solvents can be intriguing due to its unique structural characteristics. This compound generally exhibits limited solubility in water, which can be attributed to its aromatic nature and the presence of a heterocyclic pyridine ring. However, it demonstrates appreciable solubility in organic solvents.

  • Solvents where it is soluble:
    • Dimethyl sulfoxide (DMSO)
    • Dimethylformamide (DMF)
    • Ethanol
    • Acetone
  • Common solvents it is poorly soluble in:
    • Water
    • Hexane
    • Chloroform

The compound's solubility profile reflects its hydrophobic characteristics, which can influence its reactivity and interaction in various chemical environments. As a result, when working with 2-(3-pyridyl)-1,3-benzoxazole, it is best to utilize organic solvents to enhance dissolution and facilitate reactions. To summarize, “the organic solvent preference suggests potential applications in medicinal chemistry and organic synthesis where solubility plays a pivotal role.”

Interesting facts

Interesting Facts about 2-(3-Pyridyl)-1,3-benzoxazole

2-(3-Pyridyl)-1,3-benzoxazole is a fascinating compound that captures the interest of chemists and researchers alike due to its unique structure and potential applications. Here are some key points about this intriguing molecule:

  • Chemical Structure: The compound features a benzoxazole ring fused with a pyridine group. This combination not only enhances its stability but also contributes to its distinctive chemical properties.
  • Biological Significance: Numerous studies have indicated that derivatives of benzoxazole exhibit a variety of biological activities, including anti-inflammatory, antibacterial, and even potential anticancer properties. This opens doors for further exploration in medicinal chemistry.
  • Synthesis: The synthesis of 2-(3-pyridyl)-1,3-benzoxazole involves sophisticated organic reactions. Researchers often employ methods such as cyclization and condensation to achieve this compound, demonstrating the versatility and creativity required in modern organic synthesis.
  • Fluorescence Properties: One of the notable characteristics of this compound is its fluorescence. This property makes it an excellent candidate for applications in fluorescent probes and sensors, enhancing the field of biochemical detection.
  • Applications in Material Science: Beyond its biological uses, compounds like 2-(3-pyridyl)-1,3-benzoxazole are being studied for their potential in material science, particularly in the development of organic light-emitting diodes (OLEDs) and other electronic materials.

In summary, 2-(3-pyridyl)-1,3-benzoxazole is not just a compound of theoretical interest; it has practical implications in various scientific fields, making it a valuable subject for ongoing research and exploration.

Synonyms
2-pyridin-3-yl-1,3-benzoxazole
2295-42-3
BENZOXAZOLE, 2-(3-PYRIDYL)-
2-(PYRIDIN-3-YL)-1,3-BENZOXAZOLE
2-(3-Pyridyl)benzoxazole
R.750
BRN 0610288
2-(Pyridin-3-yl)benzoxazole
benzoxazole, 2-(3-pyridinyl)-
2-(pyridin-3-yl)benzo[d]oxazole
3-benzoxazolylpyridine
ChemDiv2_001661
2-(3-Pyridinyl)benzoxazole
MLS000043479
CHEMBL1477581
SCHEMBL11773057
DTXSID10177494
HMS1373L11
HMS2162L06
HMS3323H21
MFCD00168901
AKOS001693815
CCG-116142
HS-6298
SMR000020296
InChI=1/C12H8N2O/c1-2-6-11-10(5-1)14-12(15-11)9-4-3-7-13-8-9/h1-8