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2-(3-Pyridyl)quinoline-4-carboxylic acid

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Identification
Molecular formula
C15H10N2O2
CAS number
21824-89-5
IUPAC name
2-(3-pyridyl)quinoline-4-carboxylic acid
State
State

This compound is typically found in a solid state at room temperature. It is stable under normal laboratory conditions but should be stored properly to maintain its chemical integrity.

Melting point (Celsius)
243.00
Melting point (Kelvin)
516.15
Boiling point (Celsius)
536.00
Boiling point (Kelvin)
809.15
General information
Molecular weight
248.26g/mol
Molar mass
248.2570g/mol
Density
1.3450g/cm3
Appearence

2-(3-Pyridyl)quinoline-4-carboxylic acid typically appears as a white to off-white solid powder. Its crystalline form may vary, but it is often provided in powder or granulated form for laboratory and industrial uses.

Comment on solubility

Solubility of 2-(3-pyridyl)quinoline-4-carboxylic acid

The solubility of 2-(3-pyridyl)quinoline-4-carboxylic acid can be influenced by several factors such as temperature, solvent polarity, and the presence of functional groups within the compound itself. Here are some key points to consider:

  • Water Solubility: This compound generally exhibits low solubility in water due to its relatively large and complex structure, which limits its ability to interact favorably with water molecules.
  • Polar Organic Solvents: It is more soluble in polar organic solvents such as ethanol and methanol. This is largely attributed to the ability of the acid functional group to form hydrogen bonds with these solvents.
  • pH Dependency: The solubility can vary with pH; at higher pH levels, the acid can deprotonate, potentially increasing its solubility in aqueous solutions.

In summary, while 2-(3-pyridyl)quinoline-4-carboxylic acid may not be highly soluble in water, it demonstrates better solubility in polar organic solvents. Understanding the solubility behavior is critical for applications in pharmaceutical formulations and other chemical processes.

Interesting facts

Interesting Facts about 2-(3-pyridyl)quinoline-4-carboxylic Acid

2-(3-pyridyl)quinoline-4-carboxylic acid is a fascinating compound that showcases the versatility of organic chemistry. Here are some engaging insights about this intriguing molecule:

  • Structural Significance: This compound features both a quinoline and a pyridine ring, providing a complex structure that leads to unique chemical properties.
  • Pharmaceutical Potential: Substituted quinoline derivatives, such as this compound, have been studied for their pharmacological activities, including anti-inflammatory and anti-cancer properties.
  • Research Utility: It serves as a useful building block in synthetic organic chemistry. Its ability to form bonds with various reagents makes it a valuable compound for researchers developing new drugs.
  • Intermolecular Interactions: The presence of functional groups in 2-(3-pyridyl)quinoline-4-carboxylic acid influences its ability to participate in hydrogen bonding, which could be pivotal in its biological activity.
  • Applications in Coordination Chemistry: This compound can act as a ligand, forming complexes with transition metals, which are crucial in catalysis and materials science.

As researchers are continually exploring the properties and applications of compounds like 2-(3-pyridyl)quinoline-4-carboxylic acid, it opens doors to new discoveries, illustrating the dynamic nature of chemistry and its impact on various fields.

Synonyms
7482-91-9
2-(pyridin-3-yl)quinoline-4-carboxylic acid
2-(3-Pyridyl)cinchoninic acid
BRN 0206574
CINCHONINIC ACID, 2-(3-PYRIDYL)-
2-(3-Pyridyl)cinchoninsaeure
2-(3-Pyridyl)cinchoninsaeure [German]
Kyselin 2-(3-pyridyl)-cinchoninova [Czech]
4-Quinolinecarboxylic acid, 2-(3-pyridinyl)-
Kyselin 2-(3-pyridyl)-cinchoninova
DTXSID00225791
5-25-05-00235 (Beilstein Handbook Reference)
DTXCID30148282
673-275-3
2-Pyridin-3-yl-quinoline-4-carboxylic acid
2-pyridin-3-ylquinoline-4-carboxylic acid
MFCD00224806
Oprea1_361169
Oprea1_608167
SCHEMBL1901619
CHEMBL1741128
XQNXXNNXRWYNAS-UHFFFAOYSA-N
ALBB-000772
AR3155
BBL010312
STK373898
AKOS000114903
CCG-311803
SB71693
AS-45537
2-(3-pyridinyl)-4-quinolinecarboxylic acid
2-(pyridin-3-yl)quinoline-4-carboxylicacid
4-Quinolinecarboxylicacid,2-(3-pyridinyl)-
CS-0127080
EN300-00693
AB00278057-02
2-(3-PYRIDYL)-4-QUINOLINECARBOXYLIC ACID
BRD-K84699579-001-01-2
Z56780395
F0307-0468