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2-(3-Thienyl)acetic acid

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Identification
Molecular formula
C6H6O2S
CAS number
2271-90-5
IUPAC name
2-(3-thienyl)acetic acid
State
State

At room temperature, 2-(3-thienyl)acetic acid is in a solid state. It is generally stable under normal conditions of use and storage, as a powder.

Melting point (Celsius)
79.50
Melting point (Kelvin)
352.65
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
142.18g/mol
Molar mass
142.1780g/mol
Density
1.2880g/cm3
Appearence

2-(3-Thienyl)acetic acid is a compound that appears as a white to off-white crystalline powder. It possesses a faint characteristic odor and is typically handled in its solid form for chemical applications.

Comment on solubility

Solubility of 2-(3-thienyl)acetic acid

The solubility of 2-(3-thienyl)acetic acid exhibits interesting characteristics due to its unique structural features. This compound is a derivative of thienyl and contains a carboxylic acid functional group, which significantly influences its interaction with solvents.

In terms of solubility, it is noteworthy to consider the following points:

  • Polar Solvents: 2-(3-thienyl)acetic acid is generally soluble in polar solvents, such as water and ethanol. The presence of the carboxylic acid group enhances hydrogen bonding capabilities, facilitating solubility in these media.
  • Non-Polar Solvents: Conversely, the solubility in non-polar solvents, like hexane or benzene, is quite limited. The thienyl ring contributes to the hydrophobic character, which hinders interaction with non-polar environments.
  • Temperature Influence: The solubility can also be affected by temperature; as the temperature increases, the solubility in polar solvents can enhance due to increased kinetic energy leading to more effective interactions.

To sum up, the solubility of 2-(3-thienyl)acetic acid is primarily influenced by its polar carboxylic acid group, enabling better solubility in polar environments but posing challenges in non-polar systems. Understanding these aspects is essential for applications in pharmaceutical and chemical processes.

Interesting facts

Interesting Facts about 2-(3-Thienyl)acetic Acid

2-(3-Thienyl)acetic acid is a fascinating compound that belongs to the family of thienyl derivatives. Here's what makes it noteworthy:

  • Structure and Bonding: The compound features a thienyl group, which is a five-membered heterocyclic ring containing sulfur. This unique structure contributes to its reactivity and interaction with other molecules.
  • Biological Significance: Thienyl derivatives, including 2-(3-thienyl)acetic acid, have been studied for their potential biological activities. They may exhibit anti-inflammatory and analgesic properties, which makes them interesting candidates in pharmaceutical research.
  • Versatility in Synthesis: The synthesis of 2-(3-thienyl)acetic acid can involve various organic reactions, showcasing its versatility in chemical transformations. This opens doors for chemists to explore its derivatives and related compounds.
  • Applications Beyond Chemistry: Due to its structural characteristics, 2-(3-thienyl)acetic acid and its derivatives can find applications in various fields, including agrochemicals and materials science.
  • Inspiration for Research: The unique properties of this compound inspire ongoing research in various disciplines, prompting scientists to investigate its potential applications further. As one researcher noted: "The study of thienyl compounds offers endless possibilities for discovery."

In summary, 2-(3-thienyl)acetic acid stands as a testament to the intricate interplay of structure and function in organic chemistry, making it a worthwhile subject of study for both aspiring and experienced chemists.

Synonyms
3-Thiopheneacetic acid
6964-21-2
3-Thienylacetic acid
2-(thiophen-3-yl)acetic acid
3-thiophenacetic acid
2-(3-thienyl)acetic acid
thiophen-3-ylacetic acid
3-Thiopheneethanoic acid
EINECS 230-166-1
NSC 66315
BRN 0113622
3B235D2C4J
NSC-66315
DTXSID10219904
4-18-00-04066 (Beilstein Handbook Reference)
TICARCILLIN SODIUM IMPURITY B [EP IMPURITY]
TICARCILLIN SODIUM IMPURITY B (EP IMPURITY)
3Thienylacetic acid
3Thiopheneethanoic acid
DTXCID20142395
230-166-1
THIOPHENE-3-ACETIC ACID
2-thiophen-3-ylacetic acid
Thiophen-3-yl-acetic acid
MFCD00005473
thien-3-ylacetic acid
3-Thiopheneaceticacid
UNII-3B235D2C4J
3-thiopheneacetic
Ticarcillin impurity B
thiophen-3-acetic acid
3-thiophene acetic acid
thiophen-3-yl acetic acid
BIDD:GT0719
SCHEMBL351615
3-Thiopheneacetic acid, 98%
2-(thiophene-3-yl)acetic acid
2-(thiophen-3-yl)-acetic acid
RCNOGGGBSSVMAS-UHFFFAOYSA-
2-(thiophene-3-yl) acetic acid
HMS1788E07
ALBB-005997
NSC66315
BBL025878
STK503659
AKOS000119382
CS-W001140
FT34858
HY-W001140
PB28939
PS-5327
SY001354
DB-006524
DB-353135
NS00036907
T1152
EN300-17372
AI-942/25034212
3-Thiopheneacetic acid, technical, >=94.0% (T)
Q4634193
Z56922167
F2191-0124
InChI=1/C6H6O2S/c7-6(8)3-5-1-2-9-4-5/h1-2,4H,3H2,(H,7,8)