Interesting facts
Interesting Facts about 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole
This intriguing compound belongs to the family of imidazoles, a class of organic compounds that frequently appears in various biological systems and pharmaceutical applications. Here are some fascinating aspects of this compound:
- Fluorine's Influence: The presence of the trifluoromethyl group (–CF3) in its structure significantly impacts the compound's electronic properties and reactivity. This group is known for enhancing the lipophilicity of compounds, often translating to improved bioavailability in medicinal chemistry.
- Pharmacological Potential: Compounds featuring the imidazole ring are widely acknowledged for their diverse biological activities. They play vital roles in various medicinal applications, including antifungal, antibacterial, and anti-inflammatory therapies. The specific structural modifications here could yield unique therapeutics with targeted effects.
- Structural Diversity: The imidazole ring itself is a versatile scaffold that can engage in hydrogen bonding, making it an excellent candidate for drug design. Such a diverse structure could lead to exciting derivative compounds when subjected to further chemical modifications.
- Pivotal Role in Organic Synthesis: The synthesis of imidazole derivatives is a common task in organic chemistry, showcasing various methods such as condensation reactions, cyclization, and more. This compound exemplifies how researchers can modify reaction pathways to create tailored molecules for specific purposes.
- Analytical Challenge: Identifying and characterizing such compounds in laboratory settings can pose interesting challenges for chemists. Techniques such as NMR spectroscopy, mass spectrometry, and X-ray crystallography are often employed to elucidate their complex structures.
In summary, 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole is a compound with significant implications in chemical research and drug development. The unique arrangement of atoms not only contributes to its physical and chemical properties but also opens a doorway to exploring its potential in various scientific realms.
Synonyms
2-IMIDAZOLINE, 2-(m-TRIFLUOROMETHYLBENZYL)-
BRN 0915184
3038-55-9
2-(m-Trifluoromethylbenzyl)-2-imidazoline
DTXSID30184463
DTXCID40106954
5-23-07-00012 (beilstein handbook reference)
SCHEMBL953586
LRBKIWYUGFTYDU-UHFFFAOYSA-N
Solubility of 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole
The solubility of 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole is an intriguing aspect of its chemical behavior. This compound features a unique structure with a trifluoromethyl group, which can significantly influence its interaction with solvents. In general, the solubility of this compound can be affected by several key factors:
It is essential to note that “like dissolves like”; therefore, the best solvents for this compound would likely be those that share similar polarity. Some possible solvent candidates could include:
In summary, the solubility of 2-[[3-(trifluoromethyl)phenyl]methyl]-4,5-dihydro-1H-imidazole is influenced by its structural components, the polarity of the solvent, and temperature conditions. Understanding these factors is crucial for practical applications in synthesis and formulation.