2-(3,3-diphenylpropoxy)guanidine | Solubility of Things

Identification

Molecular formula

C₁₆H₁₉N₃O

CAS number

499-70-7

IUPAC name

2-(3,3-diphenylpropoxy)guanidine

State

At room temperature, 2-(3,3-diphenylpropoxy)guanidine is a solid compound, existing as a crystalline powder.

Melting point (Celsius)

198.00

Melting point (Kelvin)

471.15

Boiling point (Celsius)

420.00

Boiling point (Kelvin)

693.15

General information

Molecular weight

265.35g/mol

Molar mass

265.3500g/mol

Density

1.1495g/cm³

Appearence

2-(3,3-diphenylpropoxy)guanidine typically appears as a white to off-white crystalline powder. The compound is often used in laboratory settings and may be stored under ambient conditions when dry.

Comment on solubility

Solubility of 2-(3,3-diphenylpropoxy)guanidine

The solubility of 2-(3,3-diphenylpropoxy)guanidine can be quite intriguing, given its unique molecular structure. This compound features a guanidine group, which typically enhances solubility in polar solvents due to its ability to form hydrogen bonds. However, the presence of the bulky diphenylpropoxy group introduces considerable hydrophobic characteristics, which complicates its aqueous solubility.

Key points regarding the solubility of this compound include:

Solubility in Water: Likely to be low, primarily due to the hydrophobic nature of the diphenyl groups, making it less favorable for interaction with water molecules.
Solubility in Organic Solvents: More soluble in organic solvents like ethanol, methanol, and acetonitrile, where the lipophilic sections can interact favorably.
pH Influence: The solubility may also be pH-dependent, with the guanidine moiety being more soluble when protonated, thus enhancing its interaction with polar solvents.

Overall, while 2-(3,3-diphenylpropoxy)guanidine may have limited solubility in water, it showcases enhanced solubility in various organic solvents. In practical applications, understanding its solubility profile is crucial for optimizing formulation and use in chemical processes.

Interesting facts

Interesting Facts about 2-(3,3-diphenylpropoxy)guanidine

2-(3,3-diphenylpropoxy)guanidine is a fascinating compound that has garnered attention in various scientific fields, especially for its potential applications in medicinal chemistry and biochemistry. Here are some interesting aspects to consider:

Pharmacological Interest: This compound is often explored for its pharmacological properties, particularly in relation to its role as a guanidine derivative.
Mechanism of Action: It has been studied for its ability to modulate different biological pathways, potentially impacting conditions related to neurotransmission and regulation of physiological processes.
Structure-Activity Relationship: The presence of the diphenylpropoxy group enhances the compound's lipophilicity, which can influence its interaction with biological membranes and receptor sites.
Research Applications: Scientists are investigating its applicability in drug design, especially in developing therapeutics for neurodegenerative disorders and metabolic syndromes.
Synthesis Challenges: The synthesis of this compound requires careful consideration of reaction conditions and purification techniques, making it an intriguing subject for organic chemistry enthusiasts.

In conclusion, 2-(3,3-diphenylpropoxy)guanidine serves as a prime example of how structural modifications can lead to significant changes in biological activity. Its ongoing exploration in research highlights the dynamic nature of chemical compounds and their vast potential for innovations in health and medicine.