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Furosemide

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Identification
Molecular formula
C23H21NO5
CAS number
6856-57-5
IUPAC name
2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid
State
State

Furosemide is typically a solid at room temperature.

Melting point (Celsius)
209.00
Melting point (Kelvin)
482.15
Boiling point (Celsius)
518.30
Boiling point (Kelvin)
791.50
General information
Molecular weight
329.33g/mol
Molar mass
329.3310g/mol
Density
1.5157g/cm3
Appearence

Furosemide appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid

The solubility of a compound can significantly influence its applications in various fields, and the solubility of 2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid (C23H21NO5) is no exception. Understanding its solubility characteristics may provide insights into its behavior in different solvents and conditions.

Key Points on Solubility

  • Polarity: Due to the presence of polar functional groups, this compound may exhibit varying solubility in polar and non-polar solvents.
  • Hydrogen Bonding: The carboxylic acid group may form hydrogen bonds with water, potentially increasing solubility in aqueous solutions.
  • Aromaticity: The aromatic rings can contribute to hydrophobic interactions, possibly reducing solubility in polar environments.
  • Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, an important property in practical applications.

In summary, the solubility of C23H21NO5 is a complex interplay of its molecular structure and the solvent characteristics. Studying its solubility not only aids in understanding how to effectively utilize this compound but also sheds light on the broader principles of solvation and molecular interaction.

Interesting facts

Interesting Facts about 2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid

2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid is an intriguing compound that falls under the category of isoxazole derivatives, known for their diverse applications in medicinal chemistry. Here are some noteworthy points:

  • Pharmacological Potential: Compounds featuring the isoxazole ring have been studied extensively for their potential to treat various conditions, including inflammation, cancer, and neurological disorders. This specific structure may exhibit unique biological activities worthy of exploration.
  • Substituents Matter: The presence of methoxy groups on the phenyl rings can enhance the solubility and bioavailability of the compound. It is fascinating how minor structural variations drastically affect the compounds' activity.
  • Synthetic Pathways: The synthesis of such compounds often involves intricate organic reactions, highlighting the importance of synthetic chemistry in developing new therapeutic agents. Chemists constantly strive to create more efficient pathways to minimize costs and environmental impact.
  • Research in Progress: Ongoing studies into compounds like 2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid focus on elucidating their mechanism of action, which can lead to improved drugs with fewer side effects. As the field evolves, so does the exciting potential for new discoveries.
  • Structural Diversity: The combination of different functional groups, such as isoxazoles and carboxylic acids, emphasizes the vast diversity in chemical structures that can be explored in organic synthesis, offering tailored solutions for specific biological targets.

In conclusion, the study of 2-[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid exemplifies the beauty of organic chemistry, where the interplay of structure, function, and synthesis holds the key to scientific advancements in medicine and beyond. As scientists deepen their understanding of its properties, the potential for innovative therapeutic applications grows ever clearer.

Synonyms
mofezolac
78967-07-4
2-(3,4-bis(4-methoxyphenyl)isoxazol-5-yl)acetic acid
Mofezolac [INN]
Disopain
Mofezolaco
Mofezolacum
Mofezolac (TN)
Mofezolacum [INN-Latin]
Mofezolaco [INN-Spanish]
N-22
5-Isoxazoleacetic acid, 3,4-bis(4-methoxyphenyl)-
CCRIS 4316
UNII-RVJ0BV3H3Y
2-[3,4-bis(4-methoxyphenyl)-1,2-oxazol-5-yl]acetic acid
RVJ0BV3H3Y
BRN 5986171
DTXSID1046716
Mofezolac (JAN/INN)
[3,4-Bis-(4-methoxyphenyl)isoxazol-5-yl]-acetic acid
MOFEZOLAC [JAN]
MOFEZOLAC [MI]
3,4-bis(p-Methoxyphenyl)-5-isoxazoleacetic acid
3,4-Bis(4-methoxyphenyl)-5-isoxazoleacetic acid
MOFEZOLAC [MART.]
MOFEZOLAC [WHO-DD]
(3,4-bis(4-methoxyphenyl)-5-isoxazolyl)acetic acid
3,4-Bis((4-methoxyphenyl)-5-isooxazolyl)acetic acid
Acetic acid, 3,4-bis(4-methoxyphenyl)-5-isooxazolyl-
CHEMBL259972
DTXCID9026716
NCGC00167563-01
Mofezolacum (INN-Latin)
Mofezolaco (INN-Spanish)
MOFEZOLAC (MART.)
[3,4-bis(4-methoxyphenyl)-1,2-oxazol-5-yl]acetic acid
3,4-DMPIAA
N 22 compound
N-22 compound
[3,4-bis(4-methoxyphenyl)-5-isoxazolyl]acetic acid
Mofezolac?
(3,4-di-(4-methoxyphenyl)-5-isoxazolyl)acetic acid
CBKinase1_012222
CBKinase1_024622
Oprea1_261181
Oprea1_588700
MLS006011640
SCHEMBL151701
IFLab1_003830
[3,4-Bis-(4-methoxy-phenyl)isoxazol-5-yl]acetic acid
CHEBI:31860
DJEIHHYCDCTAAH-UHFFFAOYSA-N
HMS1422O02
Tox21_112558
BDBM50376383
EX-A11206
STK973280
AKOS000523630
CCG-107450
IDI1_009937
AC-38121
AS-68999
DA-75652
SMR000069874
CAS-78967-07-4
HY-120824
CS-0079262
NS00121011
D01718
N16836
3,4,-Di(p-methoxyphenyl)isoxazol-5-acetic Acid
[3,4-bis(4-methoxyphenyl)isoxazol-5-yl]acetic acid
BRD-K49372556-001-01-7
BRD-K49372556-001-02-5
BRD-K49372556-001-04-1
Q15409378
63X