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Oxymetazoline

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Identification
Molecular formula
C16H24Cl2N2O
CAS number
2315-02-8
IUPAC name
2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole
State
State
At room temperature, oxymetazoline is typically in its hydrochloride salt form, which is a solid. The free base form can be a liquid or solid depending on the state of purification.
Melting point (Celsius)
-10.00
Melting point (Kelvin)
263.15
Boiling point (Celsius)
445.20
Boiling point (Kelvin)
718.35
General information
Molecular weight
260.16g/mol
Molar mass
260.1580g/mol
Density
1.1200g/cm3
Appearence
Oxymetazoline appears as a clear to slightly yellowish liquid. It is typically found in its hydrochloride salt form which is more stable and soluble in water. In its pure form, it can be found as a white crystalline powder.
Comment on solubility

Solubility of 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole

The solubility of the compound 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole can be influenced by various factors, which are important to consider for both practical applications and theoretical understanding. Here are some noteworthy points about its solubility:

  • Polarity: The presence of the dichlorophenoxy group suggests a moderately polar structure, which can contribute to its interaction with polar solvents.
  • Solvent Compatibility: This compound may dissolve well in organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO), while having limited solubility in water due to hydrophobic character of the aromatic portion.
  • Temperature Effects: Like many organic compounds, its solubility can vary significantly with temperature.
    Increased temperatures often enhance solubility in organic solvents.
  • pH Influence: Depending on its ionizable groups, the solubility may also be affected by the pH of the solution, which can affect its degree of ionization.

When evaluating solubility, it's crucial to consider both the chemical structure and the environmental conditions. As stated, "the solubility of a compound provides vital information about its potential applications in various fields, from pharmaceuticals to materials science." Proper understanding of solubility can lead to more efficient usage and development of compounds like 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole.

Interesting facts

Interesting Facts About 2-[(3,4-Dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole

This fascinating compound, known for its unique structure and diverse applications, belongs to a class of chemicals that exhibit potent biological activities. Below are some engaging insights about 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole:

  • Biological Significance: The presence of both imidazole and dichlorophenoxy groups in this compound contributes to its potential as a pharmaceutical agent. Many imidazole derivatives are known for their roles as antifungal and antimicrobial agents.
  • Mechanism of Action: Compounds like this one often work by inhibiting specific enzymes or interfering with metabolic pathways in pathogens, showcasing the critical role of structure in determining biological activity.
  • Research Applications: Ongoing research into this compound focuses on understanding its effects on various biological systems, with studies aimed at discovering new therapeutic uses and enhancing its efficacy in existing applications.
  • Synthetic Potential: The synthetic routes to obtain this compound are of great interest in organic chemistry, often involving multi-step processes that reveal intricate reactions and mechanisms.
  • Environmental Impact: Compounds with similar structures can affect ecological systems, making it crucial to explore their environmental fate and the implications of their use in agriculture and industry.

In conclusion, 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole is not just a compound of interest in synthetic chemistry, but also a key player in biological research, showcasing the intricate connections between structure and function in chemical compounds.

Synonyms
FENMETOZOLE
41473-09-0
Fenmetozol
2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole
Fenmetozole [INN]
C15WFN6GMO
Fenmetozolum
1H-Imidazole, 2-((3,4-dichlorophenoxy)methyl)-4,5-dihydro-
UNII-C15WFN6GMO
Fenmetozol [INN-Spanish]
Fenmetozolum [INN-Latin]
CHEMBL50472
SCHEMBL635495
orb1703452
SCHEMBL30295426
DTXSID40194371
GLXC-06512
DH 524
AKOS022217777
NCGC00408857-02
HY-105960
NS00121455
Q5443509
2((3,4-DICHLOROPHENOXY)METHYL)-2-IMIDAZOLINE