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Clotrimazole

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Identification
Molecular formula
C22H17Cl2N
CAS number
23593-75-1
IUPAC name
2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine
State
State

Clotrimazole is a solid at room temperature.

Melting point (Celsius)
147.50
Melting point (Kelvin)
420.65
Boiling point (Celsius)
360.30
Boiling point (Kelvin)
633.45
General information
Molecular weight
312.66g/mol
Molar mass
312.6610g/mol
Density
1.2728g/cm3
Appearence

Clotrimazole is a white to pale yellow crystalline powder. It is notably tasteless and often described as having a faint odor.

Comment on solubility

Solubility of 2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine

The solubility of 2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine is influenced by several factors, and understanding them can be essential for practical applications. This compound, characterized by its unique structure, exhibits varying solubility properties in different solvents:

  • Polar Solvents: Due to the presence of the dioxane ring and amine group, this compound may be more soluble in polar solvents such as water and methanol.
  • Non-Polar Solvents: Conversely, its aromatic nature suggests limited solubility in non-polar solvents due to the hydrophobic character imparted by the chlorinated phenyl group.
  • Temperature Effects: Increasing temperature can enhance solubility, particularly in aqueous solutions, as molecular interactions become more dynamic.

It is also essential to consider the relevance of pH. The solubility of amines often increases in acidic conditions, where they can form soluble salts. When contemplating the practical usage of this compound, it's advantageous to conduct solubility tests in various environments to determine the most suitable medium for dissolution.

In summary, the solubility profile of 2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine is a complex interplay of its structural characteristics and environmental conditions. Understanding these factors can significantly affect its reactivity and usability in chemical processes.

Interesting facts

Interesting Facts about 2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine

2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine is a fascinating compound that showcases the interplay of organic chemistry and medicinal chemistry. Here are some engaging facts about this chemical:

  • Pharmacological Relevance: This compound belongs to a class of substances that has garnered interest for its potential therapeutic applications. Its unique structure may contribute to specific biological activities, although more research is often needed to fully elucidate its mechanisms of action.
  • Structural Features: The presence of the dioxane ring in its structure provides intriguing properties that can affect the reactivity and stability of the compound. The incorporation of chlorophenyl groups adds to its complexity and potential reactivity.
  • Chirality Considerations: Depending on its synthesis, this compound may exhibit chiral properties, leading to the possibility of enantiomers, which can have different biological effects. Understanding these distinctions is vital for drug development.
  • Environmental and Safety Aspects: Like many chemicals, it’s essential to consider the environmental impact and safety of handling such compounds. Understanding its behavior in different conditions is crucial for any applications.

In the words of a well-regarded chemist, “The beauty of organic chemistry lies in the endless possibilities of constructing intricate compounds with profound implications.” This statement encapsulates the essence of studying compounds like 2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine, as they represent the core of innovation in chemical research and pharmaceutical sciences.

Continued exploration in this field could potentially unveil new avenues for drug discovery, making it a captivating subject for both seasoned scientists and enthusiastic students alike.

Synonyms
17164-65-7
m-DIOXAN-5-AMINE, 2-(3,4-DICHLOROPHENYL)-5-METHYL-
5-Amino-5-methyl-2-(3,4-dichlorophenyl)-1,3-dioxane
DTXSID80169144
DTXCID6091635
2-(3,4-dichlorophenyl)-5-methyl-1,3-dioxan-5-amine
starbld0022199
2-(3,4-dichlorophenyl)-5-methyl-m-dioxan-5-amine
orb1985660
AKOS040752971