3,4-Dihydroisoquinolin-1-yl)acetamide

Identification

Molecular formula

C₁₁H₁₄N₂O

CAS number

14244-14-9

IUPAC name

2-(3,4-dihydroisoquinolin-1-yl)acetamide

State

At room temperature, 2-(3,4-Dihydroisoquinolin-1-yl)acetamide is in a solid state, typically forming crystals.

Melting point (Celsius)

109.00

Melting point (Kelvin)

382.15

Boiling point (Celsius)

390.00

Boiling point (Kelvin)

663.15

General information

Molecular weight

176.24g/mol

Molar mass

176.2150g/mol

Density

1.1900g/cm³

Appearence

2-(3,4-Dihydroisoquinolin-1-yl)acetamide appears as a white to off-white crystalline powder. The compound is relatively stable under normal conditions and may emit a slight odor typical of amides.

Comment on solubility

Solubility of 2-(3,4-dihydroisoquinolin-1-yl)acetamide

The solubility characteristics of 2-(3,4-dihydroisoquinolin-1-yl)acetamide provide insights into its potential applications and behavior in various environments. This compound is known to exhibit moderate solubility in polar solvents, which can be attributed to the presence of both the amide group and the isoquinoline structure. Here are some key points regarding its solubility:

Solvents: It shows reasonable solubility in solvents such as water and alcohols, primarily due to its ability to form hydrogen bonds.
Temperature Effects: Increasing temperature often enhances the solubility of organic compounds, and this is likely the case for 2-(3,4-dihydroisoquinolin-1-yl)acetamide.
pH Influence: The solubility may vary with pH levels, particularly if protonation or deprotonation of the amide group occurs.
Practical Considerations: When formulating with this compound, it is essential to consider the solubility limits to avoid precipitation during storage or use.

In conclusion, while 2-(3,4-dihydroisoquinolin-1-yl)acetamide presents adequate solubility in various polar environments, understanding its solubility profile is crucial for effectively utilizing this compound in chemical formulations and applications.

Interesting facts

Interesting Facts about 2-(3,4-dihydroisoquinolin-1-yl)acetamide

2-(3,4-dihydroisoquinolin-1-yl)acetamide is a fascinating compound that has garnered attention in the fields of medicinal chemistry and pharmaceuticals. Here are some intriguing aspects of this compound:

Structural Significance: The presence of both the isoquinoline moiety and the acetamide group enhances its potential therapeutic applications. Isoquinolines are known for their diverse biological activities.
Biological Activity: Compounds related to isoquinoline derivatives have been explored for their roles in treating various conditions, including neurological disorders, due to their ability to interact with neurotransmitter systems.
Potential as Drug Candidates: Many isoquinoline derivatives have been reported to exhibit anticancer, antimicrobial, and anti-inflammatory properties. This opens up exciting avenues for further research into the therapeutic effects of this compound.
Research Applications: Scientists are continually investigating how compounds like 2-(3,4-dihydroisoquinolin-1-yl)acetamide can influence biological pathways, making it a relevant subject in pharmacological studies.
Synthetic Pathways: The synthetic methods used to prepare this compound often involve multi-step organic reactions, showcasing the creativity and complexity involved in modern synthetic chemistry.

In conclusion, 2-(3,4-dihydroisoquinolin-1-yl)acetamide represents a blend of structural complexity and potential pharmacological benefits. As research continues, it may contribute to the development of new therapeutic agents and deepen our understanding of isoquinoline-based chemistry.

Synonyms

3,4-Dihydro-1-isoquinolineacetamide

19622-86-7

1-Isoquinolineacetamide, 3,4-dihydro-

DTXSID60173300

3,4-Dihydro-1-isoquinolineacetamide, monohydrochloride

DTXCID1095791

2-(3,4-dihydroisoquinolin-1-yl)acetamide

NCIOpen2_004445

1-Aminocarbonylmethyl-3,4-dihydro-isochinolin

D8L3Q6B2YG

SCHEMBL5213961

2-(3,4-dihydroisoquinolin-1-yl) acetamide