Folinic acid | Solubility of Things

Identification

Molecular formula

C₂₀H₂₃N₇O₇

CAS number

58-05-9

IUPAC name

2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid

State

At room temperature, folinic acid is typically in a solid state.

Melting point (Celsius)

175.00

Melting point (Kelvin)

448.15

Boiling point (Celsius)

936.70

Boiling point (Kelvin)

1 209.85

General information

Molecular weight

473.45g/mol

Molar mass

473.4470g/mol

Density

1.5900g/cm³

Appearence

Folinic acid appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid

This compound, with the chemical formula C₂₀H₂₃N₇O₇, exhibits interesting solubility characteristics due to its complex structure.

Key Points Regarding Solubility:

Hydrophilicity: The presence of multiple hydroxyl (-OH) groups and a phosphonooxy function suggests that this compound is likely to be highly hydrophilic, enhancing its solubility in polar solvents such as water.
Ionization: Due to the existence of acidic (carboxylic) functional groups, this compound may also undergo ionization, which can significantly improve its solubility in aqueous solutions.
Solubility in Organic Solvents: Conversely, its solubility in non-polar solvents may be limited, making it less soluble in organic solvents like hexane or chloroform.
Influence of pH: The solubility can vary with changes in pH; as a benzoic acid derivative, it may dissolve better in basic environments where deprotonation occurs.

Overall, upon considering various factors such as polarity, ionization, and environmental conditions, it can be concluded that 2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid is most soluble in polar solvents under certain conditions, particularly in neutral to basic solutions.

Interesting facts

Interesting Facts about 2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid

2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid, often referred to in the scientific community by its more manageable name, is a remarkable compound that exhibits a variety of intriguing properties and potential applications. Here are some noteworthy points to consider:

Biological Significance: This compound is structurally related to important biological molecules, potentially impacting metabolic pathways due to its amino acid and phosphonooxy functionalities.
Antioxidant Activity: The presence of multiple hydroxyl groups indicates that it may exhibit antioxidant properties, which are crucial in neutralizing harmful free radicals in biological systems.
Synthetic Routes: The synthesis of this compound can involve strategies such as functional group modification and coupling reactions, allowing chemists to explore diverse methodologies for its preparation.
Phosphate Considerations: With a phosphonooxy group, this compound may interact with biological systems similarly to phosphates, influencing enzyme activity or signal transduction.
Research Potential: Structural complexity opens pathways for drug development, as compounds like this can serve as lead compounds in pharmaceutical research aimed at various diseases.
Structure-Activity Relationship (SAR): Understanding how modifications to its structure affect biological activity can provide insights into drug design.
Ecological Relevance: Compounds with such structures are often studied for their roles in environmental health, particularly regarding how they interact with biological systems in ecosystems.

In summary, 2-[(3,4-dihydroxy-2-oxo-5-phosphonooxy-pentyl)amino]benzoic acid is not just a complex chemical structure; it’s a gateway to endless research possibilities that could bridge the worlds of chemistry, biology, and medicine. As chemists continue to unravel its mysteries, we may find this compound playing a significant role in future scientific breakthroughs.