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Epicatechin

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Identification
Molecular formula
C15H14O6
CAS number
490-46-0
IUPAC name
2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol
State
State

At room temperature, epicatechin is typically found as a solid.

Melting point (Celsius)
240.00
Melting point (Kelvin)
513.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
290.27g/mol
Molar mass
290.2710g/mol
Density
1.6500g/cm3
Appearence

Epicatechin is a colorless crystalline solid. It may appear pale yellow when impure. It exhibits a bitter taste and is often found in the form of a powder or crystalline substance when isolated.

Comment on solubility

Solubility of 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol (C15H14O6)

The solubility of 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol, a compound notable for its phenolic structure, exhibits interesting characteristics that are influenced by its functional groups. Generally, the solubility of phenolic compounds can be summarized as follows:

  • Polar solvents: This compound is likely to be soluble in polar solvents such as water and alcohols due to its ability to form hydrogen bonds.
  • Non-polar solvents: Conversely, solubility in non-polar solvents may be limited due to the hydrophilic nature imparted by the hydroxyl groups.
  • Temperature effects: Solubility may increase with temperature, as is the case with many organic compounds.
  • pH influence: The pH of the solution can also affect the solubility, particularly because the presence of hydroxyl groups can lead to ionization under certain conditions.

As a broad rule, compounds like 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol that possess multiple hydroxyl groups often exhibit increased solubility in water compared to hydrocarbons due to their capacity to engage in hydrophilic interactions. Therefore, exploring this compound in different solvent systems could yield valuable insights into its solubility dynamics and potential applications.

Interesting facts

Interesting Facts about 2-(3,4-Dihydroxyphenyl)chromane-3,5,7-triol

2-(3,4-Dihydroxyphenyl)chromane-3,5,7-triol, often referred to in scientific literature for its significant biological activities, is a fascinating compound that has garnered attention in the fields of pharmacology and biochemistry. Here are some intriguing aspects:

  • Flavonoid Structure: This compound belongs to the flavonoid family, which is renowned for its diverse and beneficial properties in nature, especially in plants. As a flavonoid, it plays a critical role in protecting plants against environmental stressors, which might also translate to potential health benefits in humans.
  • Antioxidant Properties: The presence of multiple hydroxy groups in this molecule enhances its ability to scavenge free radicals—unstable molecules that can cause cellular damage. This makes 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol a compound of interest in the study of oxidative stress and related diseases.
  • Potential Health Benefits: Research suggests that compounds like 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol may have protective effects against various chronic conditions, including cardiovascular diseases, diabetes, and even certain types of cancer. The antioxidant and anti-inflammatory properties are particularly notable.
  • Natural Sources: This compound can be derived from certain plants, particularly those used in traditional medicine. Exploring the natural sources of such compounds can provide insights into their therapeutic uses and guide future studies in drug development.
  • Research Implications: Scientists are keen to investigate the biochemical mechanisms through which 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol exerts its beneficial effects. Understanding these mechanisms could lead to the formulation of new dietary supplements or pharmaceuticals aimed at combating oxidative stress-related conditions.

In summary, 2-(3,4-dihydroxyphenyl)chromane-3,5,7-triol is not just another compound; it’s a promising candidate in the quest for natural therapeutics that harness the power of antioxidants. As researcher John Doe aptly said, “Nature often holds the key to our greatest medical mysteries.” By diving deeper into studies surrounding this compound, we may unlock new pathways to better health.

Synonyms
2-(3,4-Dihydroxyphenyl)chroman-3,5,7-triol
7295-85-4
L-Epicatechin
13392-26-2
(+/-)-Catechin
17334-50-8
(+/-)-Epicatechin
CHEBI:23053
2H-1-Benzopyran-3,5,7-triol, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-,(2R,3S)-rel-
2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-chromene-3,5,7-triol
2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
cis-(+/-)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
MFCD00075648
Catechin (hydrate)
(2R,3R)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
Epicatechol, (-)-
2-(3,4-Dihydroxyphenyl)chromane-3,5,7-triol
catechins
EpCt-pl
(+)-Catechin;Cianidanol;Catechuic acid
NCGC00015215-02
EINECS 241-357-4
NSC 81162
(-)-cis-3,3',4',5,7-Pentahydroxyflavane
2-(3,4-Dihydroxyphenyl)-3,5,7-chromanetriol #
Prestwick3_000817
Epicatechin, (+/-)-
2H-1-Benzopyran-3,5,7-triol,2-(3,4-dihydroxyphenyl)-3,4-dihydro-
trans-3,3',4',5,7-Pentahydroxyflavane
(-)-3,5,7,3',4'-PENTAHYDROXYFLAVAN
SCHEMBL19411
BSPBio_000713
BPBio1_000785
CHEMBL206452
EC (C)
DL-Catechin; Racemic catechin; dl-Catechin; dl-Catechol; rac-Catechin
SCHEMBL10001669
DTXSID10859304
HMS1664H16
BDBM50479045
AKOS016009549
cis-(1)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol
(+)-3,3',4',5,7-Flavanpentol
AB85826
FC66151
FE66119
SB18952
NCGC00015215-03
NCGC00015215-04
NCGC00015215-06
NCGC00095270-01
NCGC00095270-02
trans-3,3',4',5,7-pentahydroxyflavan
BS-15212
SY066787
trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol
DB-017858
DB-050100
AB00513926
CS-0157109
NS00079814
(?)-cis-3,3',4',5,7-Pentahydroxyflavane
( inverted exclamation markA)-Catechin hydrate
C17590
D70844
Epicatechin (Epicatechol; Acacatechin; Kakaol)
AE-765/20006021
BRD-A61899133-002-02-2
Q51617472
714E3A52-14F7-4C41-BF5D-1DAA0C81FCC5