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Methylone

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Identification
Molecular formula
C11H15NO3
CAS number
186028-79-5
IUPAC name
2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol
State
State

Methylone is generally found in a solid powdery state at room temperature.

Melting point (Celsius)
148.50
Melting point (Kelvin)
421.65
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
207.27g/mol
Molar mass
207.2690g/mol
Density
1.1290g/cm3
Appearence

Methylone typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol

The solubility of 2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol is a fascinating topic given its unique structural characteristics. This compound, featuring multiple functional groups, can exhibit varied solubility profiles depending on several factors:

  • Polarity: The presence of hydroxyl (-OH) groups indicates that the compound may have some degree of polarity, which could enhance its solubility in polar solvents such as water.
  • Non-polar characteristics: The aromatic rings and the alkyl chain may impart non-polar attributes, suggesting that it could be more soluble in organic solvents like ethanol or chloroform.
  • Temperature: As with many organic compounds, solubility can increase with temperature, allowing greater interactions with solvents at elevated levels.
  • pH influence: The compound can also be influenced significantly by the pH of the solution, which may affect the ionization of the amine group, enhancing solubility in acidic conditions.

In summary, it's essential to consider the interplay of these chemical factors while predicting the solubility outcomes. As the adage goes, “Like dissolves like”; therefore, knowing the exact nature of the solvent can lead to successful dissolution strategies for 2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol. Understanding its solubility is crucial for applications in fields such as pharmaceuticals, where solubility plays a critical role in bioavailability.

Interesting facts

Interesting Facts about 2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol

This compound, often referred to in research contexts, showcases a fascinating array of properties and potentials within the field of medicinal chemistry. It is primarily studied for its role in pharmacology, particularly in the realms of therapeutic interventions and neurochemistry.

  • Structure and Functional Groups: The molecular structure includes a key amino group, which plays a critical role in its interaction with biological systems. The presence of methoxy groups enhances its solubility in organic solvents, expanding its application possibilities.
  • Pharmacological Significance: This compound has garnered interest for its potential as a pharmacological agent. Researchers are investigating its influence on neurotransmitter systems, particularly concerning mood regulation and cognitive function.
  • Research Applications: In laboratory settings, the compound serves as a useful tool for studying:
    • Neurotransmitter transporters
    • Receptor binding profiles
    • Effects on synaptic plasticity
  • Synthesis Insights: The synthesis of this compound typically involves intricate organic reactions. These can include techniques such as:
    • N-alkylation
    • Esterification
    • Reduction reactions
  • Future Directions: As research progresses, this compound may open pathways for new therapeutic agents aimed at combating psychiatric disorders or enhancing cognitive abilities. The ongoing exploration of its structure-activity relationship (SAR) remains a vital area of study.

In summary, 2-[(3,4-dimethoxyphenyl)methylamino]-1-phenyl-propan-1-ol stands as a prominent example of the intersection between organic chemistry and pharmacology, embodying the complexities and potentials that synthetic compounds can exhibit in therapeutic contexts.