Skip to main content

2-(3,4-dimethylanilino)pyridine-3-carboxylic acid

ADVERTISEMENT
Identification
Molecular formula
C14H14N2O2
CAS number
90257-40-6
IUPAC name
2-(3,4-dimethylanilino)pyridine-3-carboxylic acid
State
State

At room temperature, 2-(3,4-dimethylanilino)pyridine-3-carboxylic acid exists in a solid crystalline state, which means it maintains a defined shape and volume without a container and can be handled as a solid substance.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
453.00
Boiling point (Kelvin)
726.15
General information
Molecular weight
212.27g/mol
Molar mass
212.2500g/mol
Density
1.3200g/cm3
Appearence

The compound appears as a crystalline solid, typically characterized by its light to pale color. It may exhibit slight variations in shade depending on the presence of impurities or the form it crystallizes in.

Comment on solubility

Solubility of 2-(3,4-dimethylanilino)pyridine-3-carboxylic acid

2-(3,4-dimethylanilino)pyridine-3-carboxylic acid has notable solubility characteristics influenced by its structural components. Understanding its solubility can be broken down into a few key points:

  • Polarity: The presence of both the pyridine ring and the carboxylic acid group contributes to its overall polarity, enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The carboxylic acid functional group (-COOH) is capable of forming hydrogen bonds with water molecules, which often aids in increasing solubility.
  • Aromatic Interactions: The aromatic structure may also play a role in solubility, as it can create stacking interactions with organic solvents, potentially leading to varied solubility depending on the solvent type.
  • Effect of Substituents: The 3,4-dimethyl substitution on the aniline part may affect sterics and electronic distribution, influencing the solubility further.

In summary, the solubility of 2-(3,4-dimethylanilino)pyridine-3-carboxylic acid is facilitated by its polar nature and functional groups that can engage in favorable interactions with solvent molecules. As a result, it is primarily soluble in polar solvents while exhibiting variable solubility in organic solvents, which may be explored further in practical applications.

Interesting facts

Interesting Facts about 2-(3,4-Dimethylanilino)pyridine-3-carboxylic Acid

2-(3,4-Dimethylanilino)pyridine-3-carboxylic acid, a compound rich in fascinating properties and applications, belongs to the family of pyridine derivatives. Here are some noteworthy aspects of this intriguing compound:

  • Structural Complexity: Its structure features a pyridine ring, a versatile heterocyclic compound known for its role in many biological systems. The presence of the 3,4-dimethylaniline moiety adds complexity and diversity to its chemical behavior.
  • Pharmaceutical Potential: Compounds with similar structures often exhibit promising properties in medicinal chemistry. Pyridine derivatives are known to play significant roles in drug discovery, acting as intermediates in the development of various therapeutic agents.
  • Biological Activities: The combination of a pyridine ring with the dimethylaniline group may lend this compound antioxidant or anti-inflammatory properties, providing possible avenues for research in health sciences.
  • Research Applications: This compound can be used in organic synthesis as a building block for more complex molecules. Its ability to engage in various chemical reactions makes it invaluable in developing new materials, dyes, and sensors.

As quoted in the field of organic chemistry, "The beauty of chemistry lies in its ability to connect seemingly simple molecules to complex biochemical pathways." This statement epitomizes how compounds like 2-(3,4-dimethylanilino)pyridine-3-carboxylic acid pave the way for innovative advancements in science and industry.

In conclusion, the fascinating chemistry of 2-(3,4-dimethylanilino)pyridine-3-carboxylic acid opens the door to numerous scientific explorations. Its structural features and potential applications highlight the importance of studying such compounds in greater depth.

Synonyms
2-[(3,4-Dimethylphenyl)amino]nicotinic acid
16396-31-9
2-(3,4-dimethylanilino)pyridine-3-carboxylic acid
MLS000029718
2-[(3,4-dimethylphenyl)amino]pyridine-3-carboxylic acid
SMR000003408
2-((3,4-Dimethylphenyl)amino)nicotinic acid
Opera_ID_580
2-(3,4-Dimethyl-phenylamino)-nicotinic acid
Oprea1_347178
CHEMBL1498405
ALBB-029004
MFCD03119356
AKOS003188767
LS-10088
2-[(3,4-Dimethylphenyl)amino]nicotinicacid
CS-0336940
NS00120651