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Trimethoxyphenoxyacetamide

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Identification
Molecular formula
C11H15NO5
CAS number
6327-67-9
IUPAC name
2-(3,4,5-trimethoxyphenoxy)acetamide
State
State
At room temperature, Trimethoxyphenoxyacetamide is a solid. It is generally stable under standard conditions and should be stored in a cool, dry place to maintain its purity and prevent degradation.
Melting point (Celsius)
149.00
Melting point (Kelvin)
422.15
Boiling point (Celsius)
385.40
Boiling point (Kelvin)
658.50
General information
Molecular weight
225.24g/mol
Molar mass
225.2370g/mol
Density
1.2180g/cm3
Appearence

Trimethoxyphenoxyacetamide is typically a white or off-white solid. It may be available in powder or crystalline form, depending on how it is processed and stored. It is commonly used in research and development, so high purity samples are usually well-defined and free-flowing.

Comment on solubility

Solubility of 2-(3,4,5-trimethoxyphenoxy)acetamide

The solubility of 2-(3,4,5-trimethoxyphenoxy)acetamide is an intriguing aspect of its chemical properties. This compound contains multiple methoxy groups, which can play a significant role in enhancing its solubilizing characteristics. Here are some key points regarding its solubility:

  • Polar Characteristics: The presence of polar functional groups like methoxy (–OCH3) increases the compound's affinity for polar solvents, especially water.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the acetamide group can lead to stronger interactions with aqueous environments, enhancing solubility.
  • Solvent Specificity: While it may be soluble in water, its solubility can be significantly affected by the choice of solvent due to the interplay of hydrophilic and hydrophobic characteristics.
  • Temperature Dependence: Like many organic compounds, the solubility of this acetamide may increase with temperature, making it important to consider the conditions in which it is used.

In conclusion, the solubility of 2-(3,4,5-trimethoxyphenoxy)acetamide is a complex interplay of its molecular structure and the solvent environment. Overall, one can predict its reasonable solubility in polar solvents, especially under elevated temperature conditions, but experimental validation is always recommended for accurate assessments.

Interesting facts

Interesting Facts about 2-(3,4,5-trimethoxyphenoxy)acetamide

2-(3,4,5-trimethoxyphenoxy)acetamide is a fascinating compound that showcases the remarkable versatility of organic chemistry. Here are some key points that highlight its significance:

  • Structure and Functionality: This compound is characterized by the presence of multiple methoxy groups, which enhances its solubility and reactivity. The substitution pattern of the phenoxy group plays a critical role in its chemical behavior and biological activities.
  • Biological Relevance: Compounds similar to 2-(3,4,5-trimethoxyphenoxy)acetamide have been studied for their potential medicinal properties. Research indicates that such compounds may exhibit anti-inflammatory, antioxidant, and anticancer activities, positioning them as candidates for pharmaceutical applications.
  • Applications in Research: This compound is often utilized in various studies and experiments, particularly in the fields of drug development and medicinal chemistry. Its unique structural features provide a great platform for modifying functional groups to investigate structure-activity relationships.
  • Synthesis and Complexity: The synthesis of 2-(3,4,5-trimethoxyphenoxy)acetamide can involve several steps of organic transformations, showcasing the intricacies of synthetic organic chemistry. Chemists often explore novel synthetic routes to improve yield and efficiency.
  • Intellectual Contribution: The study of this compound not only enriches our understanding of organic molecules but also contributes to the broader field of drug discovery, where compounds are assessed for therapeutic applications.

In conclusion, 2-(3,4,5-trimethoxyphenoxy)acetamide stands as a testament to the creativity and complexity of chemical research. It exemplifies how single molecules can open doors to new scientific discoveries and innovations.

Synonyms
BRN 2335120
VUFB-5022
3,4,5-Trimethoxyphenoxyacetamide
ACETAMIDE, 2-(3,4,5-TRIMETHOXYPHENOXY)-
24789-73-9
DTXSID00179487
RefChem:314417
DTXCID30101978
2-(3,4,5-trimethoxyphenoxy)acetamide
MLS000705792
CHEMBL1428624
HMS2519E08
NCGC00247110-01
SMR000224898
AE-641/05583043