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2-(3,4,5-trimethoxyphenoxy)acetohydrazide

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Identification
Molecular formula
C11H14N2O5
CAS number
6635-90-7
IUPAC name
2-(3,4,5-trimethoxyphenoxy)acetohydrazide
State
State

The compound is typically solid at room temperature.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.00
Boiling point (Celsius)
452.50
Boiling point (Kelvin)
725.65
General information
Molecular weight
240.25g/mol
Molar mass
240.2450g/mol
Density
1.2200g/cm3
Appearence

This compound typically appears as a crystalline solid, often in a white or off-white color. The crystals are usually fine and can be easily differentiated by their appearance.

Comment on solubility

Solubility of 2-(3,4,5-trimethoxyphenoxy)acetohydrazide

The solubility of 2-(3,4,5-trimethoxyphenoxy)acetohydrazide is influenced by the structural characteristics of the compound. Here are some key points to consider regarding its solubility:

  • Polar and Nonpolar Interactions: The presence of the trimethoxy groups enhances the polar character of the molecule, promoting its interaction with polar solvents like water.
  • Hydrophilic and Hydrophobic Balance: With varying degrees of hydrophilic (water-attracting) and hydrophobic (water-repelling) segments, solubility can be somewhat limited; therefore, it may dissolve better in organic solvents.
  • Solvent Choice: Common solvents that may effectively dissolve this compound include ethanol, dimethyl sulfoxide (DMSO), and acetone, as they can stabilize the compound's structure.
  • Temperature Dependence: Like many compounds, solubility may increase with temperature; thus, heating the solvent can aid in dissolving this material more effectively.

In summary, while 2-(3,4,5-trimethoxyphenoxy)acetohydrazide may exhibit moderate solubility in polar solvents, the precise solubility will depend greatly on the solvent's characteristics and the specific conditions used during dissolution. Understanding these factors is essential for optimal application in various chemical processes.

Interesting facts

Exploring 2-(3,4,5-trimethoxyphenoxy)acetohydrazide

2-(3,4,5-trimethoxyphenoxy)acetohydrazide is an intriguing compound that falls within the category of hydrazides. This compound is notable for several reasons:

  • Versatility in Applications: Hydrazides are often utilized in the synthesis of pharmaceuticals and agrochemicals. The presence of the trimethoxyphenoxy group can enhance biological activity and solubility, making this compound a candidate for further research in medicinal chemistry.
  • Structural Diversity: The trimethoxy moiety not only contributes to the compound's unique characteristics but may also play a role in influencing its interactions with biological targets. This makes it a point of interest for those studying structure-activity relationships.
  • Research Potential: Compounds like 2-(3,4,5-trimethoxyphenoxy)acetohydrazide have been investigated for various pharmacological properties, including antioxidant and anti-inflammatory effects. These properties can be crucial in developing new therapeutic agents.
  • Synthetic Pathways: The synthetic routes to create this compound can involve several interesting chemical reactions, highlighting the importance of hydrazine derivatives in organic synthesis. Understanding these pathways assists chemists in designing more efficient synthesis for complex molecules.

In conclusion, 2-(3,4,5-trimethoxyphenoxy)acetohydrazide represents a fascinating intersection of organic chemistry and pharmacology. As research continues, compounds like this may unlock new avenues in drug discovery and development.

Synonyms
BRN 2336792
VUFB-5029
24789-77-3
3,4,5-Trimethoxyphenoxyacetohydrazide
ACETIC ACID, (3,4,5-TRIMETHOXYPHENOXY)-, HYDRAZIDE
(3,4,5-Trimethoxyphenoxy)acetic acid hydrazide
DTXSID30179490
RefChem:316169
DTXCID60101981