Skip to main content

2-(3,4,5-Trimethoxyphenyl)cyclopropanamine

ADVERTISEMENT
Identification
Molecular formula
C12H17NO3
CAS number
198799-56-3
IUPAC name
2-(3,4,5-trimethoxyphenyl)cyclopropanamine
State
State

At room temperature, 2-(3,4,5-Trimethoxyphenyl)cyclopropanamine is a solid, specifically a crystalline powder.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.20
Boiling point (Celsius)
315.70
Boiling point (Kelvin)
588.90
General information
Molecular weight
223.27g/mol
Molar mass
223.2800g/mol
Density
1.1530g/cm3
Appearence

2-(3,4,5-Trimethoxyphenyl)cyclopropanamine typically appears as a white to off-white crystalline solid. Its physical state makes it manageable in powder form for various applications.

Comment on solubility

Solubility of 2-(3,4,5-trimethoxyphenyl)cyclopropanamine

The compound 2-(3,4,5-trimethoxyphenyl)cyclopropanamine exhibits intriguing solubility characteristics, which can be influenced by various factors. Understanding its solubility is crucial for applications in pharmaceuticals and organic synthesis.

Key Factors Affecting Solubility:

  • Polar vs. Non-Polar Solvents: This compound's solubility may vary significantly between polar and non-polar solvents. Compounds containing methoxy groups generally show increased solubility in organic solvents due to their hydrophobic nature.
  • Temperature: As with many organic compounds, an increase in temperature typically enhances solubility. This is particularly true for solid compounds as they can dissolve more readily at elevated temperatures.
  • pH Levels: The solubility can also be affected by the pH of the solution, especially if ionizable functional groups are present, which may enable the compound to dissolve better in aqueous solutions.

In general, it can be noted that:

  • The methoxy groups contribute to the compound's ability to interact with other molecules, enhancing its solubility in specific solvents.
  • The cyclopropanamine structure might introduce steric effects that can also play a role in solubility behavior.

Ultimately, while experimental data on the solubility of 2-(3,4,5-trimethoxyphenyl)cyclopropanamine may not be widely available, it is reasonable to conjecture that it will have moderate solubility in organic solvents and potential limited solubility in water due to its organic nature and functional groups. As always, empirical testing is advisable to ascertain the precise solubility profile for practical applications.

Interesting facts

Interesting Facts about 2-(3,4,5-trimethoxyphenyl)cyclopropanamine

2-(3,4,5-trimethoxyphenyl)cyclopropanamine is a fascinating compound known for its unique structural features and potential applications. Here are some notable aspects:

  • Unique Structure: This compound consists of a cyclopropane ring attached to a phenyl group with multiple methoxy substituents, giving it a distinctive three-dimensional shape that greatly influences its chemical properties.
  • Biological Activity: Compounds featuring similar structural motifs have been researched for their potential pharmacological activities, including antidepressant and antipsychotic effects. The methoxy groups can enhance the compound’s ability to interact with biological targets.
  • Synthetic Versatility: The synthesis of this compound can serve as an excellent example in organic chemistry, showcasing techniques for creating cyclopropane derivatives and how substituents can modify reactivity and selectivity.
  • Research Applications: Owing to its structural characteristics, 2-(3,4,5-trimethoxyphenyl)cyclopropanamine can be utilized as a valuable reference compound in various studies aimed at developing new therapeutic agents.
  • Emerging Interest: The ongoing research into the effects of methoxy derivatives in medicinal chemistry highlights their potential in developing safer and more effective drugs with fewer side effects.

This compound exemplifies the intricate relationship between structure and function in chemistry, making it an intriguing subject for further scientific investigation.

Synonyms
2-(3,4,5-trimethoxyphenyl)cyclopropan-1-amine
17061-21-1
3,4,5-Trimethoxytranylcypromine
BRN 2848037
2-(3,4,5-Trimethoxyphenyl)-cyclopropylamine
Cyclopropanamine, 2-(3,4,5-trimethoxyphenyl)-
CYCLOPROPYLAMINE, 2-(3,4,5-TRIMETHOXYPHENYL)-
2-(3,4,5-Trimethoxyphenyl)cyclopropanamine
DTXSID90937795
2-(3,4,5-trimethoxyphenyl) cyclopropylamine
EN300-1848414