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Nordihydroguaiaretic acid

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Identification
Molecular formula
C18H22O4
CAS number
500-38-9
IUPAC name
2-(3,7-dimethylocta-2,6-dienyl)-5,6-dimethoxy-3-methyl-benzene-1,4-diol
State
State

At room temperature, Nordihydroguaiaretic acid is in a solid state. It is usually stored in an airtight container, away from light and moisture to maintain its stability and efficacy.

Melting point (Celsius)
180.00
Melting point (Kelvin)
453.15
Boiling point (Celsius)
542.23
Boiling point (Kelvin)
815.38
General information
Molecular weight
302.37g/mol
Molar mass
302.3750g/mol
Density
1.2119g/cm3
Appearence

Nordihydroguaiaretic acid, commonly abbreviated as NDGA, typically appears as a white crystalline solid. The compound is often found in powder form and is known for its stability but can slowly darken upon exposure to light due to oxidation. It is also slightly hygroscopic, meaning it can absorb moisture from the air.

Comment on solubility

Solubility of 2-(3,7-dimethylocta-2,6-dienyl)-5,6-dimethoxy-3-methyl-benzene-1,4-diol (C18H22O4)

The solubility of the compound 2-(3,7-dimethylocta-2,6-dienyl)-5,6-dimethoxy-3-methyl-benzene-1,4-diol is influenced by its chemical structure and functional groups. This organic compound, with its complex arrangement and hydrophobic hydrocarbon chain, presents unique solubility characteristics.

Generally, we can assess the solubility of such compounds based on the following factors:

  • Polarity: The presence of the hydroxyl (-OH) groups in the structure suggests some degree of polarity, which can enhance solubility in polar solvents like water.
  • Hydrophobic regions: The long alkyl chains and multiple methoxy groups introduce hydrophobicity, potentially limiting solubility in polar solvents while increasing solubility in non-polar solvents.
  • Solvent interactions: Solubility often depends on the solvent used. For instance, in organic solvents such as ethanol or acetone, this compound may exhibit better solubility due to similar polarity.

As a result, while it can be anticipated that this compound may have moderate solubility in polar solvents due to its functional groups, it could have enhanced solubility in non-polar environments. Therefore, understanding the context of **"like dissolves like"** is crucial.

In summary, the solubility of C18H22O4 can be characterized as:

  1. Potentially soluble in polar solvents.
  2. More soluble in non-polar solvents.
  3. Dependent on specific solvent environment.

Overall, experimentation in varied solvent systems is necessary to define **exact solubility parameters** for practical applications and studies.

Interesting facts

Exploring the Wonders of 2-(3,7-Dimethylocta-2,6-dienyl)-5,6-dimethoxy-3-methyl-benzene-1,4-diol

This complex compound boasts a rich tapestry of chemical characteristics and potential applications. Here are some intriguing facts about it:

  • Structure Complexity: The compound features a multi-ring structure with various functional groups, including methoxy and hydroxyl groups, imparting unique reactive properties.
  • Natural Sources: Similar compounds are often found in essential oils and other natural products, indicating a possibility for extraction and use in natural therapies.
  • Chemical Versatility: The presence of both alkene and aromatic groups makes this compound a candidate for various chemical reactions, opening the door to synthesis methods in organic chemistry.
  • Biological Activity: Compounds with similar structures have been studied for their potential antioxidant, anti-inflammatory, and anticancer properties, which could make this compound of interest in medicinal chemistry.
  • Research Potential: With its intricate structure, it serves as an excellent case study for students learning about organic syntheses and the mechanisms of reactions involving aromatic compounds.

As noted by chemists, "The beauty of chemistry lies not only in the complexity of compounds but also in their endless possibilities for application and discovery." This compound exemplifies such beauty, inviting further exploration into its synthesis and functional mechanisms. It's a reminder of how seemingly obscure compounds can lead to groundbreaking advancements in science and technology.

Synonyms
2-(3,7-dimethylocta-2,6-dien-1-yl)-5,6-dimethoxy-3-methylbenzene-1,4-diol
DTXSID00866547
DB-216359
NS00125063