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Chlorphenoxamine

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Identification
Molecular formula
C18H22ClNO
CAS number
91-81-6
IUPAC name
2-[4-[1-(4-chlorophenyl)-1-methyl-ethyl]phenoxy]-N,N-diethyl-ethanamine
State
State

At room temperature, chlorphenoxamine is usually found in solid form.

Melting point (Celsius)
52.00
Melting point (Kelvin)
325.15
Boiling point (Celsius)
373.00
Boiling point (Kelvin)
646.15
General information
Molecular weight
326.88g/mol
Molar mass
326.8900g/mol
Density
1.1257g/cm3
Appearence

Chlorphenoxamine typically appears as white or off-white powder. It may also appear in crystalline form and is known for being odorless. Sometimes, it can be found as a solid or in solution when used in pharmaceutical contexts.

Comment on solubility

Solubility of 2-[4-[1-(4-chlorophenyl)-1-methyl-ethyl]phenoxy]-N,N-diethyl-ethanamine

The solubility of the compound 2-[4-[1-(4-chlorophenyl)-1-methyl-ethyl]phenoxy]-N,N-diethyl-ethanamine can be influenced by several factors, including its molecular structure and the nature of the solvent used.

  • Polar vs. Non-Polar Solvents: Generally, this compound's solubility is expected to be greater in non-polar solvents due to its hydrophobic character stemming from the aromatic and aliphatic portions of the molecule.
  • Temperature Effects: Solubility can increase with temperature; hence, a higher temperature may enhance the solubility of this compound in suitable organic solvents.
  • pH Sensitivity: The presence of nitrogen atoms suggests that the compound may exhibit pH-dependent behavior. In more acidic or alkaline conditions, protonation/deprotonation can alter its solubility.
  • Complexation: This compound may form complexes with various ions, potentially increasing solubility in specific media, particularly in the presence of suitable coordinating ligands.

In a general sense, one could say, "Solubility is a complex interplay between the forces of attraction and the energy required to break interactions in the solid state." Thus, predicting precise solubility requires careful evaluation of these interactions.

In summary, while we can indicate potential solubilities, specific experimental data are essential for accurate determination. The multifaceted nature of solubility in this compound makes it a fascinating subject for further investigation.

Interesting facts

Interesting Facts about 2-[4-[1-(4-chlorophenyl)-1-methyl-ethyl]phenoxy]-N,N-diethyl-ethanamine

This intriguing compound, known for its complex structure, is a member of the aminophenoxy family, which has been the subject of considerable research due to its potential medicinal applications. Here are some noteworthy aspects:

  • Pharmacological Interest: Compounds with similar structures have been investigated for their roles as pharmaceuticals, particularly in areas like antidepressants and anti-inflammatory agents.
  • Mechanism of Action: The unique combination of ethyl and phenyl groups may influence the compound’s interaction with biological receptors, potentially leading to unique physiological effects.
  • Synthetic Pathways: The synthesis of this compound often employs multi-step reactions, showcasing the beauty and complexity of organic chemistry. This involves techniques such as nucleophilic substitution and aromatic substitutions.
  • Chemical Diversity: The presence of the chlorophenyl group signifies the compound's potential versatility, which could allow for alterations to create derivatives with varying properties.
  • Structure-Activity Relationship (SAR): The modification of groups at various positions in the molecule can lead to significant changes in activity, which is a crucial concept in drug design and development.

Researchers continue to explore compounds like 2-[4-[1-(4-chlorophenyl)-1-methyl-ethyl]phenoxy]-N,N-diethyl-ethanamine to unlock new therapeutic pathways. The striking features of this compound remind us of the intricate tapestry of chemistry that underpins pharmacology and innovative drug design.

Synonyms
SB2BZ8R82O
UNII-SB2BZ8R82O
SU-11445
2-(4-(1-(4-Chlorophenyl)-1-methylethyl)phenoxy)-N,N-diethylethanamine
3155-05-3
Ethanamine, 2-(4-(1-(4-chlorophenyl)-1-methylethyl)phenoxy)-N,N-diethyl-