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N-Palmitoylglucosamine

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Identification
Molecular formula
C28H50N2O7
CAS number
116447-56-0
IUPAC name
2-[[4-[2-[2-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-5-amino-5-oxo-pentanoyl]amino]-6-(octadecanoylamino)hexanoic acid
State
State

N-Palmitoylglucosamine is a solid at room temperature. It tends to be a stable compound under standard laboratory conditions and has unique solubility characteristics depending on the solvent used.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
144.00
Boiling point (Kelvin)
417.15
General information
Molecular weight
517.68g/mol
Molar mass
517.6790g/mol
Density
1.1853g/cm3
Appearence

N-Palmitoylglucosamine is an off-white to pale yellow powder. It is often found as a crystalline solid, depending on its state of hydration, and can appear slightly waxy.

Comment on solubility

Solubility Characteristics

The solubility of the compound 2-[[4-[2-[2-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-5-amino-5-oxo-pentanoyl]amino]-6-(octadecanoylamino)hexanoic acid (C28H50N2O7) can be examined through several dimensions:

  • Polarity: This compound features multiple functional groups which contribute to its overall polarity, including amino and hydroxyl groups. The presence of these polar groups suggests a potential for solubility in polar solvents such as water.
  • Hydrophilic and Hydrophobic Balance: The octadecanoyl group introduces a long hydrophobic chain that can enhance solubility in non-polar solvents while leading to decreased solubility in aqueous environments.
  • pH Influence: The solubility may vary widely with changes in pH. At acidic or basic conditions, the ionization of the amino groups can improve solubility in water.
  • Temperature Dependency: Solubility generally increases with temperature for many compounds, and thus, heat may facilitate the dissolution of this particular compound in suitable solvents.

In conclusion, while the compound may show some solubility in polar solvents, the presence of extensive hydrophobic regions suggests that its solubility in water could be limited under standard conditions. Future empirical testing will offer a clearer understanding of its solubility profiles.

Interesting facts

Interesting Facts about 2-[[4-[2-[2-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-5-amino-5-oxo-pentanoyl]amino]-6-(octadecanoylamino)hexanoic acid

This compound, often referred to in the context of research involving complex biomolecules, exhibits a fascinating structure that embodies various functional groups and applications. Here are some intriguing aspects:

  • Peptide-like Structure: The compound features multiple amide bonds, reminiscent of peptides, indicating potential roles in biological systems, particularly within drug development and enzyme design.
  • Complex Glycosylation: The presence of a sugar moiety, specifically a tetrahydropyran, highlights the compound’s possible interactions in glycosylation reactions, which are crucial in cellular signaling and recognition processes.
  • Hydroxyl Groups: The inclusion of dihydroxy groups in its structure suggests the ability to form hydrogen bonds, enhancing the compound's solubility and reactivity in various chemical environments.
  • Fatty Acid Tail: The octadecanoyl group introduces hydrophobic character, hinting at applications in lipid-based formulations or as a surfactant, which is invaluable in drug delivery systems.
  • Potential Therapeutic Uses: Given its intricate bonding and functional groups, this compound could serve as a scaffold for pharmacological agents, targeting specific biological pathways or diseases.

Overall, the 2-[[4-[2-[2-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-4-yl]oxypropanoylamino]propanoylamino]-5-amino-5-oxo-pentanoyl]amino]-6-(octadecanoylamino)hexanoic acid compound is not just a chemical entity; it is a potential key to unlocking new avenues in therapeutic development and biomolecular research. As noted in recent studies, "the exploration of such complex structures can lead to breakthroughs in both material science and medicinal chemistry." This highlights the importance of interdisciplinary approaches in chemical research today.

Synonyms
romurtide
Muroctasin
78113-36-7
DTXSID60868466
2-[[4-[2-[2-[3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxypropanoylamino]propanoylamino]-5-amino-5-oxopentanoyl]amino]-6-(octadecanoylamino)hexanoic acid
2-({4-[2-(2-{[3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy}propanamido)propanamido]-5-amino-5-oxopentanoyl}amino)-6-(octadecanoylamino)hexanoic acid