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Folinate

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Identification
Molecular formula
C20H23N7O7
CAS number
1492-18-8
IUPAC name
2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate
State
State

Folinate is typically found as a solid at room temperature. It is available as a crystalline powder that is stable under standard conditions.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.00
Boiling point (Celsius)
272.60
Boiling point (Kelvin)
545.80
General information
Molecular weight
511.52g/mol
Molar mass
511.5150g/mol
Density
1.6700g/cm3
Appearence

Folinate is a white to slightly yellowish crystalline powder. It is practically insoluble in water and alcohol but soluble in dilute alkali solutions. The compound may appear as a solid clump if exposed to humidity.

Comment on solubility

Solubility of 2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate (C20H23N7O7)

The solubility of 2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate is characterized by several intriguing aspects:

  • Polarity: Due to the presence of multiple functional groups, including amino and carboxylate groups, the compound tends to exhibit polar characteristics, which may enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability of the amino groups to form hydrogen bonds can significantly affect solubility, potentially allowing the compound to interact favorably with water molecules.
  • pH Influence: As a carboxylic acid derivative, the solubility may vary under different pH conditions. At basic pH, the carboxyl groups may deprotonate, thus increasing solubility.
  • Temperature Dependency: Solubility could be temperature-dependent, whereby increased temperatures may enhance solubility due to enhanced molecular motion.

In conclusion, the solubility of 2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate is multifaceted and influenced by a dynamic interplay of structural and environmental factors.

Interesting facts

Interesting Facts about 2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate

This compound boasts a complex structure that reflects its significant role in medicinal chemistry and drug development. Below are some intriguing facts about this compound:

Key Features

  • Active Pharmaceutical Ingredient: The compound is often explored for its potential as an active pharmaceutical ingredient (API), particularly in therapies targeting various diseases due to its biological activity.
  • Structural Diversity: Its intricate chemical structure involves multiple functional groups, which enhances its ability to interact with biological targets.
  • Potential in Cancer Research: Research indicates that compounds with similar structures are being investigated for their efficacy in cancer treatment, showcasing the importance of pteridine derivatives in oncology.
  • Biological Activity: The presence of amino and aldehyde groups plays a critical role in the compound's reactivity and potential biological function, contributing to its therapeutic effects.

Historical Significance

The development of compounds like this one is foundational in understanding how small molecules can be designed and optimized for enhanced interaction with specific biological pathways. As researchers continue to uncover its mechanisms, the potential applications in pharmacology and biochemistry only grow.

Quotes from Experts

As noted by a leading researcher in drug development, "The complexity and diversity of synthetic compounds like this one open up numerous pathways for therapeutic exploration." Such insights highlight the importance of continuous investigation into the applications of this compound in medical science.

In summary, 2-[[4-[(2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl)methylamino]benzoyl]amino]pentanedioate is not merely a chemical entity; it epitomizes the intersection of chemistry and healthcare, with promising implications for future research and application.