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Amiodarone hydrochloride

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Identification
Molecular formula
C25H29I2NO3 · HCl
CAS number
19774-82-4
IUPAC name
2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium;chloride
State
State

Amiodarone hydrochloride is typically obtained as a crystalline solid at room temperature. It is stable under normal conditions of use and storage.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
681.79g/mol
Molar mass
681.7860g/mol
Density
1.6000g/cm3
Appearence

Amiodarone hydrochloride typically appears as a white to off-white crystalline powder. It is often used in its hydrochloride form and is usually obtained as a fine, crystalline solid.

Comment on solubility

Solubility of 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium;chloride

The solubility of the compound 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium;chloride can be quite intriguing due to its complex molecular structure. Understanding its solubility is essential for both practical applications and theoretical studies. Here are some key points to consider:

  • Solvent effects: The compound is likely to be soluble in polar solvents like water because of the presence of the quaternary ammonium group, which is known to enhance solubility through ionic interactions.
  • Hydrophobic character: The butylbenzofuran moiety may introduce hydrophobic characteristics, potentially reducing solubility in aqueous environments.
  • Temperature dependence: Solubility can be temperature-dependent; as temperature increases, solubility may also increase, particularly for complex organic molecules.
  • Concentration limits: At very high concentrations, solubility may reach a saturation point, leading to precipitation or phase separation.

In summary, while the compound's ammonium chloride component suggests a degree of solubility in polar solvents, the intricate organic structure plays a significant role in determining the overall solubility profile. Further investigations and empirical solubility tests would provide valuable insights into its behavior in different solvents.

Interesting facts

Interesting Facts About 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium;chloride

This compound presents a fascinating example of the interplay between organic chemistry and medicinal applications. It is particularly noteworthy for its unique structural features and potential uses.

Structural Characteristics

  • Complex Design: The compound includes a benzofuran moiety, which is known for its significant biological activity, particularly in medicinal chemistry.
  • Iodinated Phenoxy Group: The presence of diiodo substitutions may enhance the compound’s pharmacological efficacy by improving its binding affinity to biological targets.
  • Quaternary Ammonium Ion: The diethylammonium part makes this compound cationic, which can influence its solubility and interaction with cellular membranes.

Biological Relevance

Compounds similar to this one are often explored for their potential in antimicrobial and anticancer therapies. The incorporation of the benzofuran structure is particularly promising as research has shown that derivatives can:

  • Exhibit anti-inflammatory properties.
  • Act as inhibitors of specific enzymes involved in tumor progression.
  • Display activity against various pathogens.

Applications in Research

This compound offers exciting avenues for research in pharmacology and materials science. The exploration of its pharmacokinetics will be crucial for understanding how it behaves within biological systems. Additionally, researchers might investigate:

  • The compound's interaction with cellular pathways.
  • Methods to optimize its biodistribution.
  • Potential modifications to enhance its therapeutic index.

In summary, 2-[4-(2-butylbenzofuran-3-carbonyl)-2,6-diiodo-phenoxy]ethyl-diethyl-ammonium;chloride stands as a compelling subject for scientists due to its complex architecture and the promise it holds for future medicinal applications. The combination of organic synthesis with biological analysis opens new doors for innovative treatments in the medical field.

Synonyms
2-[4-(2-butyl-1-benzofuran-3-carbonyl)-2,6-diiodophenoxy]ethyl-diethylazanium;chloride