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Ibufenac

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Identification
Molecular formula
C13H17NO2
CAS number
1553-60-2
IUPAC name
2-[4-(2-methylallylamino)phenyl]propanoic acid
State
State
Solid at room temperature, typically encountered as a crystalline powder when refined for pharmaceutical use.
Melting point (Celsius)
77.00
Melting point (Kelvin)
350.15
Boiling point (Celsius)
381.10
Boiling point (Kelvin)
654.25
General information
Molecular weight
206.29g/mol
Molar mass
206.2610g/mol
Density
1.0975g/cm3
Appearence

Ibufenac appears as a white to off-white crystalline powder. This compound, like many carboxylic acids, is known for its distinct crystalline structure and can be described as solid with a slightly waxy touch, characteristic of many pharmaceutical-grade chemicals.

Comment on solubility

Solubility of 2-[4-(2-methylallylamino)phenyl]propanoic acid

2-[4-(2-methylallylamino)phenyl]propanoic acid, with the molecular formula C13H17NO2, exhibits interesting solubility characteristics. This compound is classified as an amino acid derivative, which often shows varied solubility based on the polarity of its functional groups.

Key points regarding its solubility include:

  • Polarity Influence: The presence of both polar (carboxylic acid) and non-polar (alkyl side chain) groups suggests that solubility can vary significantly in different solvents.
  • Aqueous Solubility: Compounds like this tend to have limited solubility in water due to the hydrophobic alkyl chain, but the potential for hydrogen bonding with water molecules via the carboxylic group can enhance solubility to some extent.
  • Organic Solvents: It is likely that 2-[4-(2-methylallylamino)phenyl]propanoic acid shows improved solubility in non-polar organic solvents, which can better solvate the hydrophobic regions of the molecule.

In conclusion, while the exact solubility profile can vary depending on the medium, it is essential to recognize the balance between hydrophilic and hydrophobic characteristics of this compound. This balance dictates the solubility behavior, making it fundamental to consider both the specific conditions of the solution and the functional groups involved.

Interesting facts

Interesting Facts about 2-[4-(2-methylallylamino)phenyl]propanoic Acid

2-[4-(2-methylallylamino)phenyl]propanoic acid, often abbreviated as a unique and complex compound, is noteworthy for its intriguing chemical structure and potential applications. As a derivative of propanoic acid, this compound showcases how structural modifications can greatly influence biological activity and chemical properties.

Key Characteristics

  • Amine Functionality: The presence of an amine group significantly enhances the compound's ability to engage in biological interactions, making it an interesting subject for pharmacological studies.
  • Phenyl Group: The phenyl moiety contributes to aromatic characteristics and affects the compound's reactivity, influencing how it interacts with other molecules.
  • Stereochemistry: As an asymmetric compound, the stereochemistry of 2-[4-(2-methylallylamino)phenyl]propanoic acid can lead to varied biological responses based on its configuration.

Potential Applications

This compound may hold promise in various fields:

  • Pharmaceutical Development: Compounds similar to this one are often examined for their potential as therapeutic agents.
  • Research in Biochemistry: Due to its unique structure, it may also be valuable in biochemical research, particularly in studying enzyme interactions and metabolic pathways.
  • Environmental Science: Understanding how such compounds interact in environmental settings can provide insight into pollution and remediation strategies.

In summary, 2-[4-(2-methylallylamino)phenyl]propanoic acid represents a fascinating bridge between the realms of organic chemistry and biological systems. Its structural intricacies not only make it a compound of interest for laboratory synthesis but also for potential real-world applications that could make a significant impact in health and science.

Synonyms
alminoprofen
39718-89-3
Minalfene
2-(4-((2-Methylallyl)amino)phenyl)propanoic acid
Alminoprofene
Alminoprofeno
Alminoprofenum
Minalfen
EB-382
rac Alminoprofen
p-((2-Methylallyl)amino)hydratropic acid
Alminoprofeno [Spanish]
EB 382
Alminoprofen [INN:JAN]
Alminoprofene [INN-French]
Alminoprofenum [INN-Latin]
Alminoprofeno [INN-Spanish]
BRN 2373633
EINECS 254-604-6
racAlminoprofen-d3
Minalfen (TN)
2-(4-((2-Methylallyl)amino)phenyl)propansaeure
0255AHR9GJ
Alminoprofen, (-)-
4-((2-Methylallyl)amino)hydratropasaeure
CHEBI:31190
Benzeneacetic acid, alpha-methyl-4-((2-methyl-2-propenyl)amino)-
2-(4-(Methallylamino)phenyl)propionic acid
Acide (methallylamino-4 phenyl)-2 propionique
2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid
ALMINOPROFEN [MI]
54362-71-9
ALMINOPROFEN [INN]
ALMINOPROFEN [JAN]
Alminoprofen, (+)-
ALMINOPROFEN [MART.]
2-[4-(2-methylprop-2-enylamino)phenyl]propanoic acid
ALMINOPROFEN [WHO-DD]
Acide (methallylamino-4 phenyl)-2 propionique [French]
alpha-Methyl-4-((2-methyl-2-propenyl)amino)benzeneacetic acid
Propionic acid, 2-(4-(methallylamino)phenyl)-
L-ALMINOPROFEN
2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propionic acid
alpha-methyl-4-[(2-methyl-2-propenyl)amino]benzeneacetic acid
1794977-21-1
Alminoprofene (INN-French)
Alminoprofenum (INN-Latin)
Alminoprofeno (INN-Spanish)
ALMINOPROFEN (MART.)
Benzeneacetic acid, alpha-methyl-4-((2-methyl-2-propenyl)amino)-, (-)-
(+/-)-Alminoprofen;EB 382; Minalfene
(+/-)-Alminoprofen
UNII-0255AHR9GJ
2-(4-((2-methylprop-2-en-1-yl)amino)phenyl)propanoic acid
2-(4-((2-methylprop-2-en-1-yl)amino)phenyl)propionic acid
(2RS)-2-((4-(2-Methylprop-2-en-1-yl)amino)phenyl)propanoic acid
(2RS)-2-{[4-(2-Methylprop-2-en-1-yl)amino]phenyl}propanoic acid
Alminoprofen (Standard)
2-(4-methylallylaminophenyl)propionic acid
Alminoprofen (JP17/INN)
alminoprofen, (+-)-isomer
SCHEMBL26940
2-(4-((2-methyl-2-propenyl)amino)phenyl)propionic acid
CHEMBL1765293
DTXSID90865968
M01AE16
FPHLBGOJWPEVME-UHFFFAOYSA-N
BCP11016
UWC97721
HY-17485R
()-Alminoprofen;EB 382; Minalfene
AKOS016014146
DB13314
NCGC00522017-01
AS-78318
DA-60933
HY-17485
CS-0009220
NS00015369
D01513
Q3612806
254-604-6