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Diflunisal

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Identification
Molecular formula
C13H8Cl2N2O4
CAS number
22494-42-4
IUPAC name
2-[4-(2,2-dichloroacetyl)anilino]-2-ethoxy-1-(4-nitrophenyl)ethanone
State
State

At room temperature, Diflunisal is in a solid state. It is often provided in pill or powder form for its medicinal uses, highlighting its stability under normal environmental conditions.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.00
Boiling point (Celsius)
508.00
Boiling point (Kelvin)
781.00
General information
Molecular weight
341.16g/mol
Molar mass
341.1560g/mol
Density
1.3640g/cm3
Appearence

Diflunisal typically appears as a white to off-white crystalline powder. Its crystalline nature is a result of the defined arrangement of its molecules, which is characteristic of its solid form. The powdered form facilitates its use in pharmaceutical formulations, as it can be easily processed into tablets or capsules.

Comment on solubility

Solubility Characteristics

The compound 2-[4-(2,2-dichloroacetyl)anilino]-2-ethoxy-1-(4-nitrophenyl)ethanone, with a complex structure, exhibits specific solubility behaviors influenced by its functional groups and overall molecular composition.

Solubility Profile

In essence, the solubility of this compound can be analyzed considering the following factors:

  • Polarity: The presence of polar groups, such as the nitro group and the ethoxy moiety, can contribute to a greater affinity for polar solvents like water.
  • Hydrophobic regions: Conversely, the aromatic rings and chloroacetyl group introduce hydrophobic characteristics, which may limit solubility in aqueous environments.
  • Solvent interactions: It is likely to dissolve well in organic solvents such as ethanol, acetone, or DMSO, which can solvate both polar and non-polar elements of the molecule.

Overall, the solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-ethoxy-1-(4-nitrophenyl)ethanone is moderate in polar solvents and better in organic solvents, reflecting a nuanced balance between its hydrophilic and hydrophobic properties.

Interesting facts

Compound Overview: 2-[4-(2,2-dichloroacetyl)anilino]-2-ethoxy-1-(4-nitrophenyl)ethanone

This compound belongs to a class of organic chemicals that incorporates unique functional groups, offering intriguing properties and potential applications. Its multifaceted structure includes both an ethoxy group and a nitrophenyl group, contributing to its reactivity and biological activity. Here are some fascinating aspects of this compound:

Key Features

  • Diverse Functional Groups: The presence of both dichloroacetyl and nitrophenyl moieties can play crucial roles in drug design and synthesis, making the compound a valuable prospect in medicinal chemistry.
  • Synthetic Utility: The intricate structure of this compound often allows it to serve as a building block for the synthesis of more complex molecules, an essential process in pharmaceutical development.
  • Biological Relevance: Compounds with nitrophenyl groups are often studied for their potential biological activities, including antimicrobial and anticancer properties, leading to exciting research opportunities.

Interesting Context

In a world where pharmaceuticals dominate, understanding compounds like this one is paramount. As researchers explore new synthetic pathways, the versatility of this compound could yield innovative therapies targeted at various health conditions. Furthermore, its environmental impact could be significant, as contaminants containing halogens like chlorine require careful assessment and management.

Quote to Inspire

As the chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." With compounds such as this, the possibilities for innovation are limitless!

This compound is not merely a product of chemistry; it embodies the intersection of science and potential human advancement, making it an exciting subject of study for chemists and biochemists alike.

Synonyms
24518-45-4
N,p-Dichloroacetylanilinoethoxy-4-nitrophenylglyoxal diacetal
RefChem:161351
2-((4-(Dichloroacetyl)phenyl)amino)-2-ethoxy-1-(4-nitrophenyl)ethanone
2-[4-(2,2-dichloroacetyl)anilino]-2-ethoxy-1-(4-nitrophenyl)ethanone
BRN 2788060
Rec-15/0209
Ketone, 2-((4-(dichloroacetyl)phenyl)amino)-2-ethoxy-1-(4-nitrophenyl)-
DTXSID90947410
Rec-15-0209
ETHANONE, 2-((4-(DICHLOROACETYL)PHENYL)AMINO)-2-ETHOXY-1-(4-NITROPHENYL)-
2,2-Dichloro-1-(4-{[1-ethoxy-2-(4-nitrophenyl)-2-oxoethyl]amino}phenyl)ethan-1-one