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Dichlorophen

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Identification
Molecular formula
C14H10Cl2O3
CAS number
97-23-4
IUPAC name
2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone
State
State

At room temperature, Dichlorophen is typically in a solid state. It possesses a crystalline structure and can be found as a powder, which is slightly soluble in water but more soluble in organic solvents.

Melting point (Celsius)
204.00
Melting point (Kelvin)
477.15
Boiling point (Celsius)
529.20
Boiling point (Kelvin)
802.35
General information
Molecular weight
344.13g/mol
Molar mass
344.1570g/mol
Density
1.4070g/cm3
Appearence

Dichlorophen appears typically as an off-white to light brown crystalline solid. It may also be available in powder or granulated form. The compound is frequently used in agricultural and veterinary applications.

Comment on solubility

Solubility of 2-[4-(2,2-Dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone

The solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone can be characterized as follows:

  • Solvent Compatibility: This compound tends to exhibit varying solubility based on the polarity of the solvent. Generally, it is more soluble in organic solvents compared to polar solvents like water.
  • Influence of Temperature: The solubility may increase with temperature, making it more soluble at elevated temperatures, which is a common property observed in many organic compounds.
  • Structural Aspects: The presence of the dichloroacetyl group and phenoxy groups influence its solubility. The hydrophilic hydroxyl group may provide some solvation in polar conditions, although steric and electronic factors suggest limited solubility in aqueous environments.

In summary, while the specific solubility values are contingent upon experimental conditions, it is essential to note that 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone generally favors solubility in non-polar to moderately polar organic solvents rather than aqueous media. As with many organic molecules, conducting solubility tests in varying conditions will provide greater insight into its solubility behavior.

Interesting facts

Interesting Facts about 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone

This compound, often referred to as a novel synthetic derivative, is significant in the realm of medicinal chemistry and pharmacology. Here are some intriguing aspects to consider:

  • Chemical Structure and Function: This compound exhibits a unique structure featuring both an aniline moiety and a phenoxyphenyl group, which are known to influence its biological activity. Such structural diversity often leads to varied interactions with biological targets.
  • Anti-Cancer Potential: Compounds with structural similarities have been studied for potential anti-cancer properties. The presence of specific substituents, such as the dichloroacetyl group, can significantly enhance the compound's ability to inhibit tumor progression.
  • Research Applications: Due to its promising pharmacological properties, researchers are exploring its potential applications in designing new drugs aimed at treating various diseases, especially where traditional therapies may fall short.
  • Mechanism of Action: Understanding how this compound interacts at the molecular level is crucial. Its potential to modulate various signaling pathways makes it a candidate for comprehensive pharmacological studies.
  • Synthetic Versatility: The synthesis of this compound involves a series of organic reactions, showcasing the creative approaches chemists can utilize to create complex molecules. This opens avenues for further modifications to enhance efficacy and reduce side effects.

In conclusion, 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenoxyphenyl)ethanone stands as a testament to the intricate relationship between chemical structure and biological activity. As researchers delve deeper, we may uncover even more secrets held within its molecular architecture, paving the way for innovative therapeutic strategies in medicine.

Synonyms
BRN 2786243
2-((4-(Dichloroacetyl)phenyl)amino)-2-hydroxy-1-(4-phenoxyphenyl)ethanone
27695-60-9
Ketone, 2-((4-(dichloroacetyl)phenyl)amino)-2-hydroxy-1-(4-phenoxyphenyl)-
ETHANONE, 2-((4-(DICHLOROACETYL)PHENYL)AMINO)-2-HYDROXY-1-(4-PHENOXYPHENYL)-
RefChem:341337
DTXSID50950364
2,2-Dichloro-1-(4-{[1-hydroxy-2-oxo-2-(4-phenoxyphenyl)ethyl]amino}phenyl)ethan-1-one