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Aclonifen

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Identification
Molecular formula
C19H13Cl2NO3
CAS number
74070-46-5
IUPAC name
2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenylphenyl)ethanone
State
State

At room temperature, aclonifen is in a solid state. It is generally used in agricultural settings as an herbicide and is typically found in granular or powdered forms.

Melting point (Celsius)
199.00
Melting point (Kelvin)
472.00
Boiling point (Celsius)
466.50
Boiling point (Kelvin)
739.70
General information
Molecular weight
354.21g/mol
Molar mass
354.1800g/mol
Density
1.3595g/cm3
Appearence

Aclonifen appears as a crystalline solid, typically having a slightly yellow to buff coloration. The compound is often encountered in its powdered form.

Comment on solubility

Solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenylphenyl)ethanone

The solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenylphenyl)ethanone in various solvents reveals significant trends:

  • Polar solvents: Generally, this compound exhibits low solubility in highly polar solvents due to its complex structure and hydrophobic regions.
  • Apolar solvents: Conversely, it shows a higher degree of solubility in non-polar solvents, which may facilitate interactions with its hydrophobic parts.
  • pH influence: The solubility can be affected by pH, as the presence of the hydroxyl group can lead to variations in solubility based on protonation states.

As a rule of thumb, if a compound has both hydrophilic and hydrophobic features, its solubility can be a balancing act, leading to:

  • Enhanced solubility in mixed polar-apolar solvent systems.
  • Reduced solubility in strictly aqueous environments.

To summarize, the solubility of this compound is context-dependent, influenced by solvent polarity, pH levels, and temperature. Thus, one must evaluate the solubility characteristics in the context of intended applications and environments.

Interesting facts

Interesting Facts about 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenylphenyl)ethanone

This unique compound, often referred to for its applications and structural characteristics, belongs to a class of chemical compounds that exhibit intriguing properties. Here are some fascinating details to consider:

  • Potential Applications: Due to its distinctive structure, this compound is investigated for its potential in pharmaceuticals, particularly in drug development. Its ability to interact with biological molecules makes it a candidate for research in medicinal chemistry.
  • Structural Features: The compound is characterized by two aromatic rings connected through an ethanone linkage, which enhances its stability and reactivity. The presence of the dichloroacetyl group introduces significant electron-withdrawing character, affecting its chemical behavior.
  • Synthetic Routes: Chemists are continually exploring pathways to synthesize this compound. The synthesis often involves multi-step reactions, allowing for modifications that can lead to analogs with varying biological activities.
  • Research Focus: Studies on this compound often focus on its mechanism of action, especially in relation to its potential anticancer properties. Understanding how it interacts with specific cellular targets can reveal insights into new treatment modalities.
  • Environmental Considerations: Research also includes examining the environmental impact of such compounds, particularly concerning their degradation and potential bioaccumulation. Understanding these factors is critical for ensuring safe use in industrial applications.

As we delve deeper into the study of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(4-phenylphenyl)ethanone, we uncover a compound rich in complexity and promise, making it a significant subject of research in contemporary chemistry.

Synonyms
BRN 2779838
27695-61-0
1-(1,1'-Biphenyl)-4-yl-2-((4-(dichloroacetyl)phenyl)amino)-2-hydroxyethanone
Ketone, 1-(1,1'-biphenyl)-4-yl-2-((4-(dichloroacetyl)phenyl)amino)-2-hydroxy-
ETHANONE, 1-(1,1'-BIPHENYL)-4-YL-2-((4-(DICHLOROACETYL)PHENYL)AMINO)-2-HYDROXY-
RefChem:340984
DTXSID10950365
1-([1,1'-Biphenyl]-4-yl)-2-[4-(dichloroacetyl)anilino]-2-hydroxyethan-1-one