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Clorindione

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Identification
Molecular formula
C17H13Cl2NO3
CAS number
6283-63-2
IUPAC name
2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(p-tolyl)ethanone
State
State

Clorindione is typically a solid at room temperature, appearing as a crystalline powder.

Melting point (Celsius)
192.00
Melting point (Kelvin)
465.15
Boiling point (Celsius)
331.30
Boiling point (Kelvin)
604.45
General information
Molecular weight
363.20g/mol
Molar mass
363.2280g/mol
Density
1.3951g/cm3
Appearence

Clorindione typically appears as a white crystalline powder. It may have a subtle, characteristic odor depending on its purity and formulation.

Comment on solubility

Solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(p-tolyl)ethanone

The solubility of 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(p-tolyl)ethanone in various solvents can provide insight into its chemical behavior and potential applications. Understanding its solubility is crucial for its use in formulations, whether in a medicinal context or as a part of chemical research.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups, such as the hydroxyl group, often enhances solubility in polar solvents like water.
  • Molecular Weight: Higher molecular weight can lead to decreased solubility in solvents due to increased intermolecular forces.
  • Sterics: Bulky groups such as p-tolyl can inhibit solubility by creating steric hindrance, affecting the ability to solvate.

As a result, 2-[4-(2,2-dichloroacetyl)anilino]-2-hydroxy-1-(p-tolyl)ethanone may exhibit:

  • Moderate solubility in **polar organic solvents**, such as ethanol and dimethyl sulfoxide (DMSO).
  • Poor solubility in **nonpolar solvents**, which is expected due to the structural characteristics imparted by the dichloroacetyl and p-tolyl groups.

Therefore, it is essential to consider these factors when evaluating the solubility of this compound for practical applications. As stated, "Solubility is not just a feature of compounds but a window into their chemical nature." Understanding these dynamics can lead to new insights and innovations in chemical applications.

Interesting facts

Interesting Facts about 2-[4-(2,2-Dichloroacetyl)anilino]-2-hydroxy-1-(p-tolyl)ethanone

This compound, known for its intricate structure and diverse applications, has garnered attention in the field of organic chemistry. Here are some intriguing insights:

  • Structural Complexity: The presence of both an acetyl group and a hydroxy group in its structure contributes to its reactivity and potential as a multifunctional compound.
  • Functional Groups: With a dichloroacetyl moiety, this compound exhibits properties typical of strong electrophiles, making it a candidate for various chemical reactions, including nucleophilic substitutions.
  • Pharmaceutical Potential: The unique combination of groups may endow it with biological activity, potentially serving as a precursor for drug development due to its ability to interact with biological targets.
  • The Aniline Derivative: Aniline derivatives are often important in dye and pharmaceutical production, highlighting the compound's importance in industrial applications.
  • Environmental Impact: The dichloroacetyl moiety raises concerns regarding environmental persistence and toxicity, prompting scientific discussions around safe handling and potential regulations.

As stated by leading researchers in medicinal chemistry, “Compounds like this represent the intersection of innovation and functionality—where simplicity meets complexity.”
Understanding the behavior and properties of such molecules opens up pathways to diverse applications in science and industry.

The ongoing exploration of this compound exemplifies the dynamic nature of chemical research and its implications for future discoveries.

Synonyms
BRN 2769082
2-((4-(Dichloroacetyl)phenyl)amino)-2-hydroxy-1-(4-methylphenyl)ethanone
27695-58-5
Ketone, 2-((4-(dichloroacetyl)phenyl)amino)-2-hydroxy-1-(4-methylphenyl)-
ETHANONE, 2-((4-(DICHLOROACETYL)PHENYL)AMINO)-2-HYDROXY-1-(4-METHYLPHENYL)-
RefChem:341336
DTXSID30950362
2,2-Dichloro-1-(4-{[1-hydroxy-2-(4-methylphenyl)-2-oxoethyl]amino}phenyl)ethan-1-one