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Oxaprozin

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Identification
Molecular formula
C18H23ClN2O
CAS number
21277-02-3
IUPAC name
2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol
State
State

At room temperature, Oxaprozin is typically found in a solid state, often as a crystalline solid or powder depending on its form and processing.

Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
627.10
Boiling point (Kelvin)
900.30
General information
Molecular weight
331.84g/mol
Molar mass
331.8240g/mol
Density
1.2560g/cm3
Appearence

Oxaprozin is a pale yellow to off-white crystalline solid. It may also appear as a yellowish powder, depending on its form and level of purity. It lacks any significant odor.

Comment on solubility

Solubility of 2-[4-[3-(2-chloro-6H-benzo<c><1>-benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol

The solubility of 2-[4-[3-(2-chloro-6H-benzo<c><1>-benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol is influenced by various factors that derive from its complex structure. Understanding its solubility can help in predicting its behavior in different environments.

Key Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl groups (–OH) in the compound contributes to its polarity, which can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly increase solubility in solvent systems capable of accepting or donating hydrogen bonds.
  • Molecular Weight: Higher molecular weight may lead to decreased solubility due to increased complexity and potential van der Waals interactions.
  • Structural Interactions: Functional groups and heterocycles can engage in various interactions (like π-π stacking), influencing solubility in organic solvents.

It is often said that "like dissolves like," indicating that the solubility of a compound will be higher in solvents that share similar polar or nonpolar characteristics. Consequently, the solubility profile of this compound is expected to vary widely based on its environment.

Practical Implications:

In pharmaceutical and chemical applications, knowing the solubility is crucial for:

  • Formulation development
  • Dosing accuracy
  • Predicting bioavailability

In summary, the solubility of 2-[4-[3-(2-chloro-6H-benzo<c><1>-benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol is determined by multiple interactions and characteristics of its molecular structure, making it a compound of interest in both research and practical applications.

Interesting facts

Interesting Facts about 2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol

This intriguing compound belongs to a class of substances that are extensively studied for their potential therapeutic benefits. Here are some key points to consider:

  • Pharmacological Potential: Compounds with piperazine substructures, such as this one, are often evaluated for their roles as potential antidepressants, antipsychotics, and anxiolytics. This makes them significant in the field of medicinal chemistry.
  • Structural Diversity: The unique combination of a piperazine ring and a benzoxepin moiety contributes to its complex chemical behavior, potentially leading to a variety of biological interactions.
  • Chirality: The presence of a chiral center in the structure can result in different pharmacological effects depending on the stereochemistry, which is critical in drug development.
  • Research Interest: Due to its complex structure, this compound offers a rich ground for research; scientists often explore its synthesis, modifications, and biological activity.
  • Real-world Applications: Understanding compounds like this can lead to advances in treatments for various neuropsychiatric conditions, underscoring the importance of continued research.

In conclusion, 2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol stands at the intersection of structure and function, representing a noteworthy subject in the ongoing quest to develop better therapeutics. Its potential applications make it a compound to watch in the evolving landscape of chemistry and pharmacology.

Synonyms
DTXSID40864461
NS00124888
2-{4-[3-(2-Chlorodibenzo[b,e]oxepin-11(6H)-ylidene)propyl]piperazin-1-yl}ethan-1-ol