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Trazodone hydrochloride

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Identification
Molecular formula
C19H22ClN5O3.2HCl
CAS number
25332-39-2
IUPAC name
2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol;dihydrochloride
State
State

At room temperature, Trazodone Hydrochloride is found in a solid state.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
418.70
Boiling point (Kelvin)
691.85
General information
Molecular weight
429.46g/mol
Molar mass
429.4630g/mol
Density
1.4772g/cm3
Appearence

Trazodone Hydrochloride appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-[4-[3-(2-chloro-6H-benzo<c><1>benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol; dihydrochloride

The solubility of a compound can significantly impact its practical applications, particularly in pharmaceuticals and chemical processes. For 2-[4-[3-(2-chloro-6H-benzo<c><1>benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol; dihydrochloride, understanding its solubility characteristics is essential.

Key Factors Influencing Solubility

  • Polarity: This compound is likely to exhibit moderate to high polarity due to the presence of ethanol and piperazine functionalities.
  • Ionic Nature: Being a dihydrochloride salt, it is expected to be soluble in polar solvents, particularly water, as the chloride ions facilitate dissolution.
  • Temperature Dependency: As with many compounds, an increase in temperature can enhance solubility, allowing more of the substance to dissolve in the solvent.

Solubility Insights

While specific solubility data for this compound might not be widely documented, it can be anticipated that:

  • It is likely highly soluble in water due to its ionic nature.
  • Solubility in organic solvents might vary, generally being better in polar solvents.
  • An understanding of the pH can also affect solubility, as changes in pH may alter the ionization state of the compound.

In conclusion, 2-[4-[3-(2-chloro-6H-benzo<c><1>benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol; dihydrochloride presents interesting solubility properties influenced by its structural characteristics. It exemplifies the interplay of ionic and polar characteristics in determining how compounds behave in solution.

Interesting facts

Interesting Facts about 2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol;dihydrochloride

This compound, commonly recognized for its intricate structure and potential biological applications, captivates the interest of both chemists and pharmacologists alike. The distinctive features of its molecular structure highlight several important aspects:

  • Complexity of Structure: The presence of a benzo[c][1]benzoxepin moiety lends significant complexity to the compound, showcasing how variations in the molecular backbone can affect its biological activity.
  • Pharmacological Potential: Compounds like this one often exhibit properties that may be beneficial in drug development, particularly in areas such as psychiatric medication and neuropharmacology.
  • Role as a Ligand: The piperazine ring acts as a key structural feature, capable of interacting with various receptors in the central nervous system, making it a subject of research in the development of novel treatments.
  • Chlorine Substitution: The chlorine atom plays a crucial role in enhancing the molecule's binding affinity and selectivity towards targeted receptors.

Additionally, researchers find the dihydrochloride salt form particularly useful in enhancing solubility and stability, crucial factors during the formulation process for potential therapeutic use.

Quote: "A deeper understanding of complex molecules like this can lead us to breakthroughs in treatment philosophies, emphasizing the interconnectedness of structure and function in medicinal chemistry."

In summary, 2-[4-[3-(2-chloro-6H-benzo[c][1]benzoxepin-11-ylidene)propyl]piperazin-1-yl]ethanol;dihydrochloride serves as a potent reminder of the vast landscape of possibilities that exist within chemical compounds and their implications in the field of medicine.

Synonyms
orb1701792