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Chlorprothixene

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Identification
Molecular formula
C18H18ClNOS
CAS number
113-59-7
IUPAC name
2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol
State
State

At room temperature, chlorprothixene is usually found as a solid due to its crystalline structure.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
415.30
Boiling point (Kelvin)
688.45
General information
Molecular weight
315.86g/mol
Molar mass
315.8520g/mol
Density
1.3000g/cm3
Appearence

Chlorprothixene typically appears as a yellow crystalline solid or powder. The specific form it takes can vary, but it is generally identifiable by its distinctive yellow color.

Comment on solubility

Solubility of 2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol

The solubility of the compound 2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol can be influenced by several factors, including its chemical structure and the surrounding environment.

Generally, one might consider the following aspects when evaluating solubility:

  • Polarity: The presence of hydroxyl (-OH) groups increases polarity, potentially enhancing solubility in polar solvents like water.
  • Hydrophobic Regions: The thioxanthen compound may create hydrophobic regions, suggesting limited solubility in aqueous solutions.
  • pH Dependency: The solubility might vary with pH, particularly if protonation or deprotonation affects the compound’s charge status.

Based on these characteristics, it might be anticipated that:

  • In polar solvents, solubility could be moderate to high due to hydrogen bonding capabilities of the hydroxyl group.
  • In non-polar solvents, solubility is likely to be minimal, given potential hydrophobic interactions from the thioxanthen moiety.

In conclusion, while specific solubility data may be required for precise applications, understanding the balance between polar and non-polar characteristics provides valuable insight into how 2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol may behave in various environments.

Interesting facts

Interesting Facts about 2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol

This intriguing compound is a member of the piperazine family, known for its wide range of applications in medicinal chemistry, particularly in the development of pharmaceuticals. Its unique structure not only gives it potential therapeutic properties but also contributes to its complexity, making it an interesting subject of study.

Key Features

  • Medicinal Chemistry: The presence of a piperazine ring often enhances the compound's ability to interact with various biological targets, making it a candidate for drug development.
  • Chlorothioxanthen-9-ylidene Moiety: This group is associated with numerous biologically active compounds and may impart special properties, such as enhanced binding affinity or selectivity for specific receptors.
  • Versatility: The incorporation of ethanol in its composition suggests potential solubility and bioavailability benefits, making it a compound of interest in formulating effective drugs.

From a synthetic perspective, the challenges involved in creating such a diverse compound can lead to the development of novel methodologies and techniques. One interesting quote that highlights the significance of such compounds is:

“The best way to predict the future is to invent it.” – Alan Kay

In exploring compounds like 2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol, chemists are constantly pushing the boundaries of what is possible in drug design. The investigation of its pharmacological properties could open doors to new treatments for various diseases, reinforcing the compound's relevance in modern chemistry.

Synonyms
2-[4-[3-(2-chlorothioxanthen-9-ylidene)propyl]piperazin-1-yl]ethanol
(Z)-Clopenthixol
2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol
AY 62021
C22H25ClN2OS
NSC64087
Prestwick0_000998
Prestwick1_000998
SCHEMBL121819
SPBio_002986
AAA98224
AKOS030242398
NCI60_013633
NS00114130
NS00126286
Q413000