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Carbamazepine

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Identification
Molecular formula
C15H12N2O
CAS number
298-46-4
IUPAC name
2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate
State
State
Carbamazepine is typically found in a solid state at room temperature. It is frequently utilized in the form of oral tablets or capsules, which are designed for sustained or immediate release in the medical treatment of specific conditions.
Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
335.00
Boiling point (Kelvin)
608.15
General information
Molecular weight
256.27g/mol
Molar mass
256.2680g/mol
Density
1.2296g/cm3
Appearence

Carbamazepine typically appears as a white or off-white crystalline powder. It may also be available in a tablet form for medical applications. The compound is practically odorless and has a bitter taste. It is known for its stability and is only slightly soluble in water, making it a convenient pharmaceutical compound for oral administration.

Comment on solubility

Solubility of 2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate

The solubility of 2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate can be quite complex due to its intricate molecular structure. Here are some factors that influence its solubility:

  • Polarity: The presence of multiple functional groups can affect the overall polarity of the compound. Its solubility in polar solvents (like water) may be limited while showing better solubility in organic solvents.
  • Hydrogen Bonding: The capability for hydrogen bonding, particularly related to the methoxymethyl group and the carbamate functionality, can enhance solubility in polar solvents.
  • Temperature: As with many chemical compounds, solubility can vary with temperature. Generally, increased temperature increases solubility, especially in solids.
  • pH Levels: The solubility may also depend on the pH of the solvent, as changes in pH can affect ionic and molecular interactions, altering solubility.

Overall, understanding the solubility of this compound is essential for its application in pharmacology and material science. As noted, its behavior in various solvents could be significant for both practical usage and further research: "The solubility profile of a compound often dictates its bioavailability and therapeutic potential."

Interesting facts

Interesting Facts about 2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate

This compound is a fascinating example of a complex molecular structure that merges elements of pharmacology and organic chemistry. Below are some key points that highlight its significance:

  • Pharmacological Potential: Compounds like this one are often investigated for their potential as therapeutic agents, particularly in the treatment of psychiatric disorders due to the presence of a phenothiazine moiety, which is known for its antipsychotic properties.
  • Structure-Activity Relationship: The intricate design of the molecule allows scientists to study how different parts of the compound contribute to its biological activity. The piperazine and carbamate components can influence both solubility and receptor affinity.
  • Combining Chemistry with Medicine: This compound embodies the crossover between chemistry and medicine, illustrating how a deep understanding of molecular interactions can lead to the development of new drugs.
  • Complexity and Synthesis: The synthesis of such complex compounds involves careful consideration of reaction conditions and mechanisms. This makes it a great learning opportunity for chemistry students to understand synthetic routes and strategies.
  • Interdisciplinary Research: Research on this compound spans multiple disciplines, including organic chemistry, medicinal chemistry, and neuropharmacology, making it a rich subject for interdisciplinary collaboration.

As chemists continue to explore compounds like 2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate, they not only advance our understanding of chemical properties but also pave the way for innovations in therapeutic practices. The exploration of such compounds is crucial for developing new and effective medicines.

Synonyms
2-[4-[3-[2-(methoxymethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl N,N-dimethylcarbamate
DTXSID90274935