Interesting facts
Interesting Facts about 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl acetate
This fascinating compound belongs to the family of phenothiazine derivatives, which are structurally significant in medicinal chemistry. Here are some key points to consider about this intriguing compound:
- Pharmacological Interest: Compounds containing phenothiazine structures have been extensively studied for their roles as antipsychotic medications. They often exhibit a range of therapeutic activities, making them significant in treating various mental health disorders.
- Trifluoromethyl Group: The presence of the trifluoromethyl group is noteworthy. This substituent can greatly enhance the biological activity and metabolic stability of the molecule, allowing it to interact more efficiently with biological targets.
- Piperazine Linkage: The inclusion of a piperazine ring is crucial for maintaining the necessary interactions within cellular environments. This moiety can improve the binding affinity to receptors, enhancing therapeutic efficacy.
- Esters in Medicinal Chemistry: The acetate functional group not only provides potential for improved solubility but may also act as a prodrug, altering the activity profile of the parent compound when metabolized in vivo.
As noted by many researchers, "The chemistry of phenothiazines offers a window into the intricate relationship between structure and function in medicinal compounds." This underscores the importance of such compounds in the pursuit of new therapeutic agents.
This compound exemplifies how a careful balance of structural modifications can lead to enhanced medicinal properties. Its design reflects the innovative spirit of modern chemistry, where the exploration of new compounds continues to pave the way for impactful medical advancements.
Synonyms
2021-89-8
O-Acetylfluphenazine
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)propyl)-, acetate
5NU56V4LR8
4-(3-(2-(Trifluoromethyl)phenothiazin-10-yl)propyl)-1-piperazineethanol acetate
NSC-226515
1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-10H-phenothiazin-10-yl)propyl)-, acetate (ester)
NSC 226515
BRN 0731494
2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl acetate
UNII-5NU56V4LR8
1-Piperazineethanol, acetate
DTXSID70174060
VZXRBTTXAUZWBO-UHFFFAOYSA-N
NSC226515
1-Piperazineethanol, acetate (ester)
WLN: T C666 BN ISJ EXFFF B3- AT6N DNTJ D2OV1
4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol 1-Acetate; 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-, acetate (ester) (9CI); 1-Piperazineethanol, 4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]-, acetate (6CI,7CI,8CI); NSC 226515
Solubility of 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl acetate
The solubility of 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethyl acetate can be quite intriguing due to its complex structure. Understanding the solubility characteristics of this compound can provide insights into its potential applications in various chemical, pharmaceutical, and biological contexts.
Factors Affecting Solubility
Several factors influence the solubility of this compound:
General Solubility Insights
Although specific solubility data for this compound may not be readily available, it is interesting to propose that:
The interplay of these effects indicates that solubility is a multifaceted property, often requiring practical experimentation to ascertain precise values. As a reminder, "like dissolves like," meaning that finding the appropriate solvent can be key to achieving successful dissolution of this intriguing compound.