Interesting facts
Interesting Facts About 2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
This fascinating compound is a member of the thioxanthenes, a class of compounds known for their complex aromatic structures and significant biological activity. Here are some intriguing facts about this particular molecule:
- Medicinal Applications: Due to its unique structure, this compound is of interest in pharmacology. Compounds resembling thioxanthene have been investigated for their potential as antipsychotic medications.
- Fluorine's Role: The presence of the trifluoromethyl group (–CF3) enhances the compound's biological properties and lipophilicity, increasing membrane permeability.
- Structure-Activity Relationships: Researchers often explore how modifications to the thioxanthenic core influence pharmacological effects, paving the way for the development of novel therapeutic agents.
- Versatile Substituents: The piperazine moiety in this compound is known for its versatility in medicinal chemistry, often serving as a framework for enhancing drug activities through various substitutions.
- Research Potential: The compound’s complex structure and unique functional groups make it a prime candidate for further investigation in drug design and synthetic chemistry.
In summary, 2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol serves as an exemplary compound for studying structural effects on biological activity, showcasing the intricate relationship between chemistry and medicinal application. As research evolves, this compound may pave the way for innovative treatments in the field of psychiatry.
Synonyms
Flupentixol
FLUPENTHIXOL
2709-56-0
2-[4-[3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol
Flupentiol
2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
Prestwick0_000340
Prestwick1_000340
SPBio_002300
CHEMBL4743867
DTXSID3058749
NJMYODHXAKYRHW-UHFFFAOYSA-N
NS00076284
Q27164953
(ez)-2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
Solubility of 2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
The solubility of a chemical compound is influenced by various factors, including its molecular structure, polarity, and the nature of the solvent. In the case of 2-[4-[3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol, we can make some interesting observations:
To sum up, while the presence of the alcohol group suggests potential for solubility in polar solvents, the bulky and hydrophobic nature of the thioxanthenyl structure and trifluoromethyl group might limit its overall solubility in aqueous solutions. Therefore, experimental solubility testing is recommended to ascertain precise solubility characteristics in various solvent systems.