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Diethylcarbamazine citrate

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Identification
Molecular formula
C15H34N4O4 • 2Cl
CAS number
90-89-1
IUPAC name
2-[4-[[3-[4-[2-(diethylammonio)ethoxycarbonyl]anilino]-3-oxo-propanoyl]amino]benzoyl]oxyethyl-diethyl-ammonium;dichloride
State
State

At room temperature, this compound is a solid. It is stable under standard conditions and does not react with air. Its stable nature makes it suitable for use in medicinal chemistry and pharmaceutical formulations.

Melting point (Celsius)
138.00
Melting point (Kelvin)
411.15
Boiling point (Celsius)
291.00
Boiling point (Kelvin)
564.15
General information
Molecular weight
493.85g/mol
Molar mass
493.8510g/mol
Density
1.1304g/cm3
Appearence

This compound typically appears as a white to off-white crystalline powder, commonly used in pharmaceutical applications. The crystalline structure is fine, and it may sometimes appear as granules depending on the method of preparation.

Comment on solubility

Solubility of 2-[4-[[3-[4-[2-(diethylammonio)ethoxycarbonyl]anilino]-3-oxo-propanoyl]amino]benzoyl]oxyethyl-diethyl-ammonium;dichloride

The solubility of this compound can be characterized by several key factors:

  • Polarity: Due to the presence of multiple polar functional groups, including ammonium and ether linkages, this compound is likely to exhibit good solubility in polar solvents, particularly water.
  • Ionic Nature: As a quaternary ammonium salt, the diethylammonium component contributes to its ionic nature, enhancing solubility in aqueous solutions.
  • Alkyl Chains: The diethyl groups may introduce some hydrophobic characteristics, which can affect solubility in more nonpolar solvents. However, the dominant polar characteristics are expected to prevail.

Overall, one can expect this compound to demonstrate:

  1. High solubility in water, making it suitable for use in aqueous formulations.
  2. Limited solubility in organic, nonpolar solvents due to the ionic, polar nature dominating the structure.

In summary, as a highly polar, ionic compound, 2-[4-[[3-[4-[2-(diethylammonio)ethoxycarbonyl]anilino]-3-oxo-propanoyl]amino]benzoyl]oxyethyl-diethyl-ammonium;dichloride is expected to be markedly soluble in water, affirming its potential utility in various aqueous applications.

Interesting facts

Interesting Facts about 2-[4-[[3-[4-[2-(diethylammonio)ethoxycarbonyl]anilino]-3-oxo-propanoyl]amino]benzoyl]oxyethyl-diethyl-ammonium; dichloride

This compound is a fascinating example of a quaternary ammonium compound, which showcases the intersection of organic chemistry and medicinal applications. Here are some engaging insights:

  • Complex Structure: Its intricate structure comprises multiple functional groups, including an anilino structure and an ethoxycarbonyl moiety, which contribute significantly to its reactivity and potential biological activity.
  • Biological Activity: Compounds like this one often play a critical role in pharmaceutical formulations due to their ability to target specific biomolecules, making them essential in drug design and therapy.
  • Ion Exchange Properties: Being a quaternary ammonium compound, it possesses strong cationic properties, allowing it to interact with negatively charged cellular components, which can be useful in drug delivery systems.
  • Applications in Research: This compound’s unique structure provides researchers with valuable insights into mechanisms of action, particularly in understanding interactions at the molecular level.
  • Potential Side Effects: As with many chemically complex compounds, it is essential to consider potential toxicity and side effects, making thorough research and testing indispensable before clinical applications.

Overall, 2-[4-[[3-[4-[2-(diethylammonio)ethoxycarbonyl]anilino]-3-oxo-propanoyl]amino]benzoyl]oxyethyl-diethyl-ammonium; dichloride encapsulates the vibrant world of chemical compounds, where structure and function merge seamlessly. As we delve deeper into its properties and effects, new possibilities in medicinal chemistry continue to emerge.

Synonyms
Novdimal
14722-97-5
N,N'-malonylbisprocaine dihydrochloride
2-[4-[[3-[4-[2-(diethylazaniumyl)ethoxycarbonyl]anilino]-3-oxopropanoyl]amino]benzoyl]oxyethyl-diethylazanium;dichloride
N,N'-Malonyl-bis-novocaine dihydrochloride
Benzoic acid, 4,4'-(malonylidiimino)di-, bis(2-(diethylamino)ethyl) ester, dihydrochloride
Bis(2-(diethylamino)ethyl) 4,4'-((1,3-dioxo-1,3-propanediyl)diimino)bisbenzoate dihydrochloride
Benzoic acid, p,p'-malonyldiiminodi-, bis(2-(diethylamino)ethyl) ester, dihydrochloride
Benzoic acid, 4,4'-((1,3-dioxo-1,3-propanediyl)diimino)bis-, bis(2-(diethylamino)ethyl) ester, dihydrochloride