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Folic acid

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Identification
Molecular formula
C19H19N7O6
CAS number
59-30-3
IUPAC name
2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid
State
State

At room temperature, folic acid is found in a solid state, specifically as a crystalline powder.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
441.40g/mol
Molar mass
441.4040g/mol
Density
1.6800g/cm3
Appearence

Folic acid typically appears as a yellow or orange-yellow, crystalline powder. It is practically insoluble in water and slightly soluble in alcohol. Upon exposure to air and light, it can degrade, leading to changes in appearance.

Comment on solubility

Solubility of 2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid

The solubility of the compound 2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid (C19H19N7O6) is influenced by a variety of factors, primarily due to its complex structure and functional groups.

Factors Affecting Solubility:

  • Polarity: This molecule contains both polar and nonpolar regions, which can affect how it interacts with solvents.
  • pH Dependence: The carboxylic acid groups present may lead to variable solubility in different pH environments.
  • Hydrogen Bonding: The presence of nitrogen and oxygen atoms may facilitate hydrogen bonding with the solvent, enhancing solubility in polar solvents.
  • Molecular Weight: The relatively high molecular weight may impede solubility due to limited diffusion rates in solution.

In general, this compound may demonstrate moderate solubility in aqueous solutions, particularly at acidic pH due to the protonation of amine groups and the ionization of carboxylic acid groups. However, its overall solubility will heavily depend on the solvent characteristics.

Practical Considerations:

When working with this compound, consider the following:

  1. Testing solubility in a variety of solvents, such as water, ethanol, and DMSO.
  2. Evaluating dissolution rates at different temperatures to understand thermal effects.
  3. Assessing the impact of different pH levels on solubility as it can influence the ionization of acidic groups.

In summary, while 2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid exhibits promising solubility characteristics, thorough testing is essential to optimize conditions for its application.

Interesting facts

Interesting Facts about 2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid

This compound is a fascinating example of a complex organic molecule that plays a vital role in medicinal chemistry. Here are some intriguing points to note:

  • Medicinal Potential: This compound features a unique structure that suggests potential applications in drug development, particularly in targeting specific enzymes and receptors associated with various diseases.
  • Structural Complexity: The incorporation of an imidazo-pteridine moiety indicates that this compound may exhibit interesting biological activities, possibly relating to its ability to interact with nucleic acids or proteins.
  • Multifunctional Components: The combination of amino acids and carboxylic acid groups provides this compound with multifunctional properties, enhancing its ability to form various interactions in biological systems.
  • Research Interest: Given its structure, compounds like this one are often studied for their potential implications in treatments for diseases such as cancer and infectious illnesses.

As a student or chemist, one cannot overlook the significance of how subtle changes in molecular structure can lead to vastly different biological activities. As noted by renowned chemists, "The function of a molecule is determined not just by the atoms it contains, but by how those atoms are arranged."
This principle is embodied in the intricate design of 2-[[4-(3-amino-1-oxo-4,5,6,6a,7,9-hexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid, which makes it a prime candidate for further research and exploration!