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Dacinostat

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Identification
Molecular formula
C18H27ClN2O4
CAS number
1030612-90-8
IUPAC name
2-[4-[[(3,4-diethoxybenzoyl)amino]methyl]phenoxy]ethyl-methyl-ammonium;chloride
State
State

At room temperature, Dacinostat is generally observed in a solid state.

Melting point (Celsius)
138.90
Melting point (Kelvin)
412.05
Boiling point (Celsius)
355.10
Boiling point (Kelvin)
628.25
General information
Molecular weight
373.92g/mol
Molar mass
373.9200g/mol
Density
1.1900g/cm3
Appearence

Dacinostat typically appears as a crystalline solid. The compound may vary in color from white to off-white depending on its purity and specific formulation.

Comment on solubility

Solubility of 2-[4-[[[3,4-Diethoxybenzoyl]amino]methyl]phenoxy]ethyl-methyl-ammonium;chloride

The solubility of the compound 2-[4-[[[3,4-diethoxybenzoyl]amino]methyl]phenoxy]ethyl-methyl-ammonium;chloride is influenced by several factors, making it a compelling subject for study:

  • Polar Nature: The presence of the quaternary ammonium group contributes to a more polar character, enhancing its solubility in polar solvents, particularly aqueous environments.
  • Chain Length: The diethoxy group introduces hydrophobic characteristics that can affect its solubility; hence, the balance between the polar and non-polar parts defines its overall solubility behavior.
  • Electrostatic Interactions: Being a salt, the chloride ion significantly impacts the solubility, as ionic interactions promote dissolution in water.

Furthermore, it is interesting to note that:

  • Temperature Dependency: The solubility may vary with temperature, often increasing as kinetic energy favors dissolving processes.
  • pH Influence: Changes in pH can alter the ionization state of the ammonium group, which can enhance or hinder solubility.

In conclusion, understanding the solubility of this compound requires a comprehensive analysis of its structural components and environmental conditions. As with many compounds, a detailed study can reveal both intriguing patterns and practical implications for its use in various applications.

Interesting facts

Interesting Facts about 2-[4-[[(3,4-diethoxybenzoyl)amino]methyl]phenoxy]ethyl-methyl-ammonium;chloride

This compound is a fascinating entity in the world of organic chemistry, showcasing the interplay of different functional groups and their potential applications. Here are some intriguing aspects to consider:

  • Complex Structure: The compound features an intricate structure that includes both phenoxy and amide functionalities, which can strongly influence its reactivity and interactions with biological systems.
  • Potential Pharmaceutical Applications: Due to the presence of the diethoxybenzoyl moiety, this compound may show promise in drug development, particularly as an intermediary or active ingredient in therapeutics targeting various diseases.
  • Stability and Reactivity: The presence of a positively charged ammonium group suggests that this compound may be soluble in a variety of solvents, which could influence its stability and reactivity under different conditions.
  • Research Interest: Compounds with such a complex architecture are not just chemically interesting; they are often subjects of research in fields such as biochemistry and medicinal chemistry, where understanding structure-activity relationships is crucial.
  • Learning Opportunities: For students and novice chemists, studying this compound provides an excellent opportunity to learn about functional group behavior, organic synthesis techniques, and the evaluation of biological activity.
  • Environmental Considerations: As research into environmentally sustainable chemicals grows, understanding compounds like this one, including their degradation pathways, is essential in the design of greener alternatives.

Indeed, the study of compounds like 2-[4-[[[3,4-diethoxybenzoyl)amino]methyl]phenoxy]ethyl-methyl-ammonium;chloride not only enhances our knowledge of organic chemistry but also paves the way for innovative scientific advancements. As chemists, we continually seek to unravel the mysteries embedded within such complex molecules!

Synonyms
Ro 5-6574 hydrochloride
19457-00-2
UNII-Z057QA6RBJ
N-(4-(2-Methylaminoethoxy)benzyl)-3,4-diethoxybenzamide hydrochloride
RO-5-6574 hydrochloride
Z057QA6RBJ
BENZAMIDE, 3,4-DIETHOXY-N-(4-(2-METHYLAMINOETHOXY)BENZYL)-, HYDROCHLORIDE
Benzamide, 3,4-diethoxy-N-4-(2-(methylamino)ethoxy)phenylmethyl hydrochloride
BENZAMIDE, 3,4-DIETHOXY-N-(P-(2-(METHYLAMINO)ETHOXY)BENZYL)-, MONOHYDROCHLORIDE
BENZAMIDE, 3,4-DIETHOXY-N-((4-(2-(METHYLAMINO)ETHOXY)PHENYL)METHYL)-, HYDROCHLORIDE (1:1)
BENZAMIDE, 3,4-DIETHOXY-N-((4-(2-(METHYLAMINO)ETHOXY)PHENYL)METHYL)-, MONOHYDROCHLORIDE
RefChem:202885