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Cholic acid

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Identification
Molecular formula
C24H40O5
CAS number
81-25-4
IUPAC name
2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid
State
State

At room temperature, Cholic acid is in a solid state, appearing as a white crystalline or powdery substance owing to its fixed and crystalline structure.

Melting point (Celsius)
200.00
Melting point (Kelvin)
473.15
Boiling point (Celsius)
333.00
Boiling point (Kelvin)
606.15
General information
Molecular weight
408.57g/mol
Molar mass
408.5730g/mol
Density
1.0792g/cm3
Appearence

Cholic acid appears as a white crystalline solid and may also be found in powder form. It is hygroscopic, meaning it can absorb moisture from the air. Occasionally, it appears like a slightly creamy powder or granules.

Comment on solubility

Solubility of 2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid

The solubility characteristics of 2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid can be quite intriguing. This compound, due to its complex structure, presents certain solubility traits that are essential to understand for applications in pharmaceuticals and biochemistry.

Key Points of Solubility:

  • Polarity: The presence of hydroxyl (–OH) groups tends to increase solubility in polar solvents like water.
  • Molecular Weight: High molecular weight may hinder solubility in organic solvents but can enhance solubility in certain buffered solutions.
  • Hydrophobic Regions: The tetradecahydro-cyclopenta structure suggests a hydrophobic character, which could lead to limited solubility in aqueous environments.

As a general observation, compounds like this can exhibit:

  1. Increased solubility in organic solvents compared to water.
  2. Potential for pH-dependent solubility, where a change in pH could enhance or restrict solubility based on protonation states.
  3. Temperature effects, where increased temperature may vary solubility behavior.

In conclusion, the solubility of 2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid is influenced by a multitude of factors including molecular structure, polarity, and environmental conditions. Understanding these factors aids in predicting its behavior in various applications.

Interesting facts

Interesting Facts about 2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid

This complex chemical compound, known for its intricate structure, holds a significant place in various fields of scientific research, particularly in medicinal chemistry and pharmacology. Here are some captivating aspects of this compound:

  • Biological Relevance: The compound exhibits potential pharmacological properties, making it a candidate for further study in drug development.
  • Synthetic Pathways: The synthesis of this molecule can showcase innovative techniques in organic chemistry, due to its multiple chiral centers and functional groups.
  • Structure-Activity Relationship: Its structural nuances present great opportunities to explore how small modifications can impact biological activity.
  • Chirality: With several chiral centers, this compound can exist in multiple stereoisomeric forms, making chirality a crucial aspect of its study and application.
  • Potential Therapeutics: Compounds like this are often investigated for their ability to interact with various biological targets, particularly in treating complex diseases.

The complexity of the compound's name reflects its unique structure and highlights the challenges encountered in the synthesis and study of such molecules. As scientists continue to unlock the potential of this compound, it may pave the way for breakthroughs in various therapeutic areas, emphasizing the interconnectedness of chemical structure and biological activity. Stay tuned for more insights as research unfolds!

Synonyms
SCHEMBL15049403
CHEBI:181446
2-[4-[(3R,5R,10R,12S,13R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentylamino]acetic acid
N-(3,12-Dihydroxycholan-24-yl)glycine