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Sulfoxaflor

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Identification
Molecular formula
C10H15ClNO4
CAS number
946578-00-3
IUPAC name
2-[4-[4-(4-chlorophenoxy)phenyl]sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid
State
State

At room temperature, sulfoxaflor is in the form of a solid crystal. Its stability in this state makes it suitable for agricultural applications where it is used effectively as an insecticide.

Melting point (Celsius)
158.50
Melting point (Kelvin)
431.65
Boiling point (Celsius)
575.50
Boiling point (Kelvin)
848.65
General information
Molecular weight
277.68g/mol
Molar mass
277.6790g/mol
Density
1.4700g/cm3
Appearence

Sulfoxaflor is typically a white or off-white crystalline solid. It is a chemical compound often used as an insecticide. Its crystalline form allows it to be handled easily in various applications.

Comment on solubility

Solubility of 2-[4-[4-(4-chlorophenoxy)phenyl]sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid (C10H15ClNO4)

The solubility of 2-[4-[4-(4-chlorophenoxy)phenyl]sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid can be influenced by various factors due to its complex structure. Here are some key points to consider:

  • Polarity: The presence of polar hydroxamic acid functional groups may enhance its solubility in polar solvents such as water.
  • Functional Groups: The chlorophenoxy and sulfonyl groups can affect the intermolecular interactions, which in turn influence solubility.
  • Solvent Interaction: Solubility can vary in different solvents, potentially being more soluble in organic solvents like methanol or DMSO due to reduced hydrogen bonding compared to water.
  • Saturation Point: The precise solubility limits can depend on temperature and concentration, making it essential to conduct experimental studies to determine exact values.

In summary, while the solubility of this compound is likely to be influenced by its unique chemical structure, it remains important to experimentally validate solubility in target solvents to optimize its application.

Interesting facts

Interesting Facts about 2-[4-[4-(4-chlorophenoxy)phenyl]sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid

This compound, known as a hydroxamic acid derivative, presents an intriguing blend of structural complexity and biological activity. Here are some fascinating insights into its characteristics:

  • Biological Significance: Hydroxamic acids are widely recognized for their ability to inhibit metalloproteinases, which are enzymes that can degrade the extracellular matrix. This property makes them potential candidates in therapeutic applications, especially in cancer treatment and wound healing.
  • Structural Components: The molecule features a tetrahydropyran ring, which is a cyclic ether known for its stability and role in various natural products. Additionally, the presence of a chlorophenoxy group highlights its utility in developing pharmaceuticals with targeted biological properties.
  • Environmental Impact: Compounds with chlorinated phenyl groups are often studied for their environmental behavior due to their persistence and potential bioaccumulation. Understanding this compound can lead to insights regarding safe disposal methods and environmental risks.
  • Drug Development: The multifunctional nature of hydroxamic acids, combined with substituents like the sulfonyl group, opens pathways for the synthesis of novel drugs. Research continues to explore how modifications to its structure can enhance selectivity and reduce side effects when used in therapeutic contexts.
  • Synthesis Challenges: The complexity of synthesizing such a compound can be daunting. The process often involves multistep reactions, requiring careful selection of reagents and conditions to ensure high yields and purity.

In summary, the study of 2-[4-[4-(4-chlorophenoxy)phenyl]sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid showcases how intricate molecular designs can lead to a diverse range of functionalities, opening doors for exciting developments in the fields of biochemistry and medicinal chemistry.

Synonyms
2-{4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-TETRAHYDRO-PYRAN-4-YL}-N-HYDROXY-ACETAMIDE
CHEMBL93687
2-{4-[4-(4-chlorophenoxy)benzenesulfonyl]oxan-4-yl}-N-hydroxyacetamide
2-(4-(4-(4-chlorophenoxy)benzenesulfonyl)oxan-4-yl)-N-hydroxyacetamide
2-(4-(4-(4-Chloro-Phenoxy)-Benzenesulfonyl)-Tetrahydro-Pyran-4-Yl)-N-Hydroxy-Acetamide
SCHEMBL4314591
456c
rs113456
BDBM50146636
DB02049
4-[4-(4-CHLORO-PHENOXY)-BENZENESULFONYL]-4-METHYL-TETRAHYDRO-PYRAN;COMPOUND WITH N-HYDROXY-ACETAMIDE
PD008190
NS00069333
Q27093136
2-(4-{[4-(4-chlorophenoxy)phenyl]sulfonyl}tetrahydro-2H-pyran-4-yl)-N-hydroxyacetamide