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Tamoxifen

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Identification
Molecular formula
C26H29ClNO
CAS number
60-24-2
IUPAC name
2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]-N,N-dimethyl-ethanamine
State
State
At room temperature, tamoxifen is a solid.
Melting point (Celsius)
97.00
Melting point (Kelvin)
370.15
Boiling point (Celsius)
585.15
Boiling point (Kelvin)
858.30
General information
Molecular weight
371.88g/mol
Molar mass
371.5110g/mol
Density
1.1240g/cm3
Appearence

Tamoxifen typically appears as a white or off-white crystalline powder.

Comment on solubility

Solubility Profile of 2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]-N,N-dimethyl-ethanamine

When evaluating the solubility of the compound 2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]-N,N-dimethyl-ethanamine (C26H29ClNO), several factors come into play that influence its behavior in various solvents. Though specific solubility data may be limited, we can make some general observations:

  • Polar vs. Nonpolar Solvents: This compound contains both polar (such as the amine group) and nonpolar (aromatic rings) characteristics. Therefore, it is likely to be soluble in polar aprotic solvents, while its nonpolar components work well with organic solvents like hexane.
  • Aromatic Solubility: The presence of multiple aromatic rings suggests that it may dissolve well in aromatic solvents such as toluene or xylene due to favorable π-π interactions.
  • Temperature Dependence: Like many organic compounds, solubility can increase with temperature. This could potentially enhance its dissolution in organic solvents.

In summary, while comprehensive solubility data is essential for practical applications, it is reasonable to suggest that 2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]-N,N-dimethyl-ethanamine would display varied solubility depending on the solvent type, mainly favoring organic and aromatic environments.

Interesting facts

Interesting Facts about 2-[4-(4-Chloro-1,2-diphenyl-but-1-enyl)phenoxy]-N,N-dimethyl-ethanamine

This compound is a fascinating member of the family of amines and displays intriguing characteristics that are of particular interest to scientists and researchers.

Key Characteristics

  • Versatile Applications: This compound can play a significant role in medicinal chemistry. Its structure positions it for potential use in drug development and pharmaceuticals, particularly in targeting specific receptors due to its unique functional groups.
  • Chirality: The presence of asymmetric carbon centers in its structure could lead to stereoisomerism, which is critical in understanding the pharmacodynamics of the compound.
  • Substituted Aromatics: The combination of aromatic rings along with the chloro substituent could enhance its reactivity and interaction with biological systems, making it a point of study for various chemical reactions.

Research Implications

Due to its intricate structure, scientists are excited about its potential implications in research. The compound can be studied for:

  1. Mechanistic studies: Understanding how the compound interacts on a molecular level with biological molecules.
  2. Therapeutic potential: Investigating its effectiveness as a therapeutic agent in treating different diseases, especially owing to the combined effects of its structural components.
  3. Environmental impact: Analyzing the compound's stability and biodegradability could provide insights on its environmental footprint.

As we unravel the complexities of organic compounds like this one, we are reminded of the overarching theme in chemistry: the relationship between structure and function. Thus, every novel compound has the potential to lead to breakthrough discoveries.

Synonyms
89778-26-7
(E)-Toremifene
2-[4-(4-chloro-1,2-diphenylbut-1-enyl)phenoxy]-N,N-dimethylethanamine
89778-29-0
SCHEMBL906278
CHEMBL3185138
DTXSID20861115
(2-{4-[(1E)-4-CHLORO-1,2-DIPHENYLBUT-1-EN-1-YL]PHENOXY}ETHYL)DIMETHYLAMINE
BCP07809
AB89554
NCGC00160530-03
NCI60_004916
DB-057163
Q27164641
(Z)-2-(4-(4-Chloro-1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethanamine
2-{4-[(1E)-4-Chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethan-1-amine