2-(4-(4-chlorophenyl)piperazin-1-yl)ethyl cinnamate

Identification

Molecular formula

C₂₁H₂₃ClN₂O₂

CAS number

38656-24-7

IUPAC name

2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate

State

This compound is typically found as a solid at room temperature.

Melting point (Celsius)

107.00

Melting point (Kelvin)

380.15

Boiling point (Celsius)

489.50

Boiling point (Kelvin)

762.65

General information

Molecular weight

385.88g/mol

Molar mass

385.8800g/mol

Density

1.1498g/cm³

Appearence

2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate is a white to off-white solid that may crystallize in different forms depending on conditions.

Comment on solubility

Solubility of 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate

The solubility of 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate is an important factor to consider in both pharmaceutical applications and chemical processes. Understanding its solubility characteristics can provide insight into its behavior in different environments. Here are some key points regarding its solubility:

Solvent Type: This compound is likely to exhibit varying solubility in polar versus non-polar solvents, given its complex structure.
Temperature Dependence: Like many organic compounds, its solubility may increase with temperature, allowing for higher concentrations in solution.
pH Influence: The solubility can also be affected by pH levels, especially if the compound contains functional groups that can ionize.
Hydrophobic Interactions: The presence of aromatic rings may lead to significant hydrophobic interactions, potentially reducing its solubility in aqueous solutions.

In laboratory settings, it's crucial to conduct systematic solubility tests to ascertain optimal conditions for dissolving 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate. This approach can lead to improved formulations and better comprehension of its reactivity and stability in various environments.

Interesting facts

Interesting Facts about 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate

This fascinating compound, known for its potential pharmacological applications, offers a glimpse into the intricate world of medicinal chemistry. Here are some captivating insights:

Pharmacological Significance: The compound is a derivative of piperazine, which is frequently found in numerous pharmaceutical drugs, showcasing its importance in developing medications, especially for mental health and neurological disorders.
Structure-Activity Relationship (SAR): The presence of both a piperazine ring and a phenylprop-2-enoate moiety enables chemists to study the impact of these structural features on the biological activity, leading to improved drug design.
Chlorophenyl Group: The introduction of a chlorophenyl group increases the lipophilicity of the compound, enhancing its ability to cross biological membranes, which is crucial for therapeutic efficacy.
Versatile Intermediates: Compounds like this one often serve as intermediates in the synthesis of more complex molecules, allowing for the fine-tuning of pharmacological properties through synthetic modifications.
Research Potential: Scientists are continually exploring the ability of this compound to modulate neurotransmitters, particularly in conditions such as depression and anxiety, opening avenues for novel treatment options.

In summary, 2-[4-(4-chlorophenyl)piperazin-1-yl]ethyl 3-phenylprop-2-enoate exemplifies the fascinating intersection of chemistry and medicine. Its structural complexity and potential therapeutic applications make it an exciting subject of ongoing research and study in the realm of drug development.