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Identification
Molecular formula
C19H21NO5S
CAS number
493104-90-2
IUPAC name
2-[4-(4-phenoxyphenyl)sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid
State
State
The compound is solid at room temperature, typically appearing as a stable crystalline powder.
Melting point (Celsius)
223.50
Melting point (Kelvin)
496.65
Boiling point (Celsius)
550.00
Boiling point (Kelvin)
823.15
General information
Molecular weight
403.44g/mol
Molar mass
403.4700g/mol
Density
1.2800g/cm3
Appearence

The compound appears as a white crystalline solid.

Comment on solubility

Solubility of 2-[4-(4-phenoxyphenyl)sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid

The compound 2-[4-(4-phenoxyphenyl)sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid (C19H21NO5S) exhibits unique solubility characteristics that are influenced by its functional groups and overall structure.

Solubility Properties

  • Polar Character: The presence of hydroxamic acid functional group is known to enhance water solubility due to its ability to form hydrogen bonds.
  • Hydrophobic Moieties: However, the bulky phenoxy group introduces hydrophobic characteristics, which may lead to limited solubility in polar solvents.
  • Solvent Dependent: Overall solubility might vary significantly in different solvents. For instance, it may dissolve better in organic solvents such as methanol or ethanol compared to water.
  • pH Influence: The solubility can also be affected by the pH of the solution, potentially increasing in more alkaline conditions.

As a rule of thumb, compounds with both hydrophilic and hydrophobic regions often possess amphiphilic properties, leading to a solubility profile that can be both fascinating and complex. Therefore, assessing solubility requires careful consideration of the solvent environment.

Interesting facts

Interesting Facts About 2-[4-(4-phenoxyphenyl)sulfonyltetrahydropyran-4-yl]ethanehydroxamic acid

This compound is a fascinating example of a complex organic molecule characterized by a unique structure that includes both a hydroxamic acid functional group and a sulfonyl group. It belongs to a class of compounds that have garnered attention in medicinal chemistry for their potential biological activities.

Key Features:

  • Hydroxamic Acid: The presence of the hydroxamic acid group makes this compound a probable inhibitor for certain enzymes such as metalloproteinases, thus suggesting potential applications in cancer therapy and tissue remodeling.
  • Sulfonyl Group: The sulfonyl moiety enhances the compound's reactivity, potentially allowing it to interact with various biological targets.
  • Phenoxyphenyl Unit: The intricate phenoxyphenyl structure contributes to the compound's overall biological activity and may influence its pharmacokinetics.

What makes this compound particularly interesting is its structural diversity, which could lead to:

  • Enhanced selectivity for specific biological targets, resulting in fewer side effects in therapeutic use.
  • Development of novel pharmaceuticals through structure-activity relationship studies.

As scientists further explore the implications of this compound in drug design, it opens up new horizons for research in targeted therapy and personalized medicine. The potential impacts of this compound on health care are truly promising!

Synonyms
n-hydroxy-2-[4-(4-phenoxy-benzenesulfonyl)-tetrahydro-pyran-4-yl]-acetamide
CHEMBL1235735
N-hydroxy-2-(4-(4-phenoxybenzenesulfonyl)oxan-4-yl)acetamide
N-hydroxy-2-[4-(4-phenoxybenzenesulfonyl)oxan-4-yl]acetamide
N-Hydroxy-2-(4-(4-phenoxy-benzenesulfonyl)-tetrahydro-pyran-4-YL)-acetamide
RS2
SCHEMBL7307897
966c
BDBM50028942
AKOS040746308
DB08491
193022-38-7
PD004352
NS00069517
Q27097692
N-hydroxy-2-{4-[(4-phenoxyphenyl)sulfonyl]tetrahydro-2H-pyran-4-yl}acetamide