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Roxarsone

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Identification
Molecular formula
C6H6AsN2O3S
CAS number
121-19-7
IUPAC name
[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
State
State

Roxarsone is usually found in a solid state at room temperature. Due to its crystalline structure, it maintains its solid form unless subjected to conditions reaching its melting point. This stability under ambient conditions makes it suitable for storage and handling in typical laboratory settings.

Melting point (Celsius)
229.00
Melting point (Kelvin)
502.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
263.06g/mol
Molar mass
263.0620g/mol
Density
1.7400g/cm3
Appearence

Roxarsone appears as a white to yellowish crystalline solid. It may also appear off-white depending on the purity and form it is found in. Its crystalline nature provides a distinctive sheen and structure that can be observed under a microscope. This compound is relatively stable under standard conditions.

Comment on solubility

Solubility of 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol

The solubility of the compound 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol is a critical aspect that influences its practical applications.

Factors Influencing Solubility

The solubility of this compound can be affected by several factors:

  • Polarity: The presence of both dithiarsolan and methanol functional groups introduces a level of polarity, which may enhance solubility in polar solvents like water.
  • Temperature: Temperature often plays a significant role, as higher temperatures can generally increase solubility.
  • pH Levels: Changes in pH can affect ionization states, thereby influencing solubility. For instance, basic conditions might improve the solubility of amine-containing compounds.

General Observations

In general, the solubility characteristics of complex chemical structures can be summarized as follows:

  • Typically, compounds that contain extensive hydrogen bonding and polar groups exhibit good solubility.
  • Conversely, highly hydrophobic regions can lead to reduced solubility in aqueous environments.

It is essential to note that while preliminary observations may suggest potential solubility, detailed experimental investigations are necessary to accurately determine the solubility profile of this compound under various conditions.

Interesting facts

Interesting Facts about 2-[4-[(4,6-Diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol

This compound, characterized by its complex structure, interestingly combines elements that are foundational in organic and inorganic chemistry. It showcases a unique amalgamation of triazine and dithiarsolane moieties, which can be pivotal in various applications.

Chemical Features

  • Diversity of Elements: The presence of sulfur and nitrogen atoms in the compound introduces unique properties, making it very interesting for research on sulfur-containing organic compounds.
  • Biological Significance: Compounds like this one are often studied for their potential biological activities, particularly in fields like medicinal chemistry, where they might exhibit anti-cancer properties or serve as targeted drug delivery agents.
  • Complexity of Structure: The intricate structure, with multiple functional groups, makes it an excellent subject for studying structure-activity relationships (SAR) in drug development.

Research Potential

Researchers are increasingly focused on compounds with complex architectures akin to this one due to their potential for:

  • Multi-target interactions: The ability to interact with multiple biological pathways could lead to more effective therapeutic agents.
  • Environmentally friendly applications: There is a growing interest in compounds that can be biodegradable or have minimal environmental impact.

Conclusion

The exploration of 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol exemplifies the intricacies of chemical synthesis and the endless opportunities for discovery within chemical compounds. As research advances, this compound may very well illuminate new pathways in pharmacology and materials science.

Synonyms
MELARSOPROL
494-79-1
Mel B
Melarsoprolum
Melarsoprolum [INN-Latin]
RP 3854
EINECS 207-793-4
Melarsoprol [INN:BAN:DCF]
[2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-1,3,2-dithiarsolan-4-yl]methanol
Melarsoprol (INN)
UNII-ZF3786Q2E8
RP-3854
ZF3786Q2E8
MELARSOPROL [MI]
Mel B (TN)
MELARSOPROL [INN]
MELARSOPROL [MART.]
MELARSOPROL [WHO-DD]
DTXSID90862033
2-(p-(4,6-Diamino-s-triazin-2-ylamino)phenyl)-1,3,2-dithiarsolane-4-methanol
1,3,2-Dithiarsolane-4-methanol, 2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-
Melarsoprolum (INN-Latin)
(2-(4-((4,6-diamino-1,3,5-triazin-2-yl)amino)phenyl)-1,3,2-dithiarsolan-4-yl)methanol
MELARSOPROL (MART.)
(2-{4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl}-1,3,2-dithiarsolan-4-yl)methanol
1,3,2-Dithiarsolane-4-methanol, 2-[4-[(4,6-diamino-1,3,5-triazin-2-yl)amino]phenyl]-
DTXCID00810863
P01CD01
207-793-4
Arsobal
CHEBI:6729
Melarsoprol(Mixture of Diastereomers)
Specia
CHEMBL166
SCHEMBL61707
JCYZMTMYPZHVBF-UHFFFAOYSA-N
AKOS040752991
Melarsoprol (Mixture of Diastereomers)
DB12864
HY-119594
CS-0070029
NS00080111
C08001
D00832
Q419753
2-[4-{(4,6-Diamino-1,3,5-triazin-2-yl)amino}phenyl]-1,3,2-dithiarsolan-e-4-methanol