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Diethylcarbamazine

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Identification
Molecular formula
C19H24ClN3O4S
CAS number
90-89-1
IUPAC name
2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine
State
State

The compound is typically found in a solid state as a white or off-white crystalline powder at room temperature.

Melting point (Celsius)
86.00
Melting point (Kelvin)
359.15
Boiling point (Celsius)
425.90
Boiling point (Kelvin)
699.00
General information
Molecular weight
267.80g/mol
Molar mass
267.8000g/mol
Density
1.1655g/cm3
Appearence

The compound appears as a white to off-white crystalline powder, odorless or with a faint characteristic odor. It is usually available in this solid form and may have a bitter taste.

Comment on solubility

Solubility of 2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine

The solubility of 2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine is influenced by various factors due to its complex structure. This compound is known to exhibit moderate solubility in certain organic solvents.

Factors Affecting Solubility:

  • Polarity: The compound features both polar and nonpolar regions within its molecular structure, which contributes to its solubility characteristics in different solvents.
  • Hydrophobic Interactions: The presence of the benzothiazole ring and diethyl groups can enhance hydrophobic interactions, potentially limiting solubility in water.
  • Hydrogen Bonding: The ability to form hydrogen bonds may facilitate solubility in alcohols or other polar solvents.

Generally, it is noted that:

  • Water: Limited solubility is expected due to the compound's hydrophobic attributes.
  • Organic Solvents: Increased solubility in common organic solvents such as ethanol or dimethyl sulfoxide (DMSO).

In conclusion, while the solubility of 2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine may vary based on the solvent and environmental conditions, it predominantly favors organic solvents over aqueous solutions. This characteristic plays a crucial role in its applications and reactivity in various chemical processes.

Interesting facts

Interesting Facts about 2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine

This compound, known for its complex structure and fascinating properties, is a member of a larger class of chemical compounds that often exhibit biological activity. Here are some intriguing aspects:

  • Pharmaceutical Potential: Its unique structure makes it a candidate for research in pharmacology. Compounds with benzothiazole backbones are often explored for their anti-inflammatory, antibacterial, and antifungal properties.
  • Chlorine as a Functionality: The presence of chlorine in the benzothiazole ring can significantly influence the compound's reactivity and bonding characteristics, making it a focal point in synthetic and medicinal chemistry.
  • Phenoxy Group Insights: The phenoxy functional group contributes to its ability to interact with biological systems, often enhancing the compound's solubility and organic profile.
  • Isoform Specificity: Research suggests that structural modifications like those found in this compound can affect its interaction with specific biological targets, potentially leading to selective action that is critical in drug development.
  • Synthetic Routes: The synthesis of this compound involves sophisticated organic reactions, highlighting the creativity and skill of chemists in developing novel compounds from basic precursors.

In summary, 2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethyl-ethanamine represents an exciting blend of chemistry and biology, revealing a multitude of research paths. As scientists continue to explore its properties, we can expect to uncover more about its potential applications in therapeutic settings.

Synonyms
HALETAZOLE
Halethazole
Haletazol
Haletazole [INN]
Haletazolum
UNII-U89MCO87LX
HALETHAZOLE [MI]
HALETAZOLE [WHO-DD]
DTXSID2048406
5-Chlor-2-(4-(2-diethylaminoethoxy)phenyl)benzothiazol
5-Chloro-2-[p-(diethylaminoethoxy)phenyl]benzothiazole
5-Chloro-2-(p-(diethylaminoethoxy)phenyl)benzothiazole
DTXCID0028379
txokwxjqvfuudd-uhfffaoysa-n
Episol
15599-36-7
2-[4-(5-chloro-1,3-benzothiazol-2-yl)phenoxy]-N,N-diethylethanamine
U89MCO87LX
5-Chloro-2-(p-(2-diethylaminoethoxy)phenyl)benzothiazole
NCGC00160568-01
5-Chloro-2-[p-(2-diethylaminoethoxy)phenyl]benzothiazole
SCHEMBL151076
CHEMBL1397608
CHEBI:135524
NS00125544
Q27290863