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N-Acetylanthranilic acid

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Identification
Molecular formula
C10H11NO3
CAS number
5571-99-9
IUPAC name
2-(4-acetamidophenyl)acetic acid
State
State

At room temperature, 2-(4-acetamidophenyl)acetic acid is a solid.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
179.19g/mol
Molar mass
179.1850g/mol
Density
1.3486g/cm3
Appearence

2-(4-Acetamidophenyl)acetic acid appears as a white to off-white crystalline powder. It is relatively stable when stored in a cool, dry place away from light.

Comment on solubility

Solubility of 2-(4-acetamidophenyl)acetic acid

The compound 2-(4-acetamidophenyl)acetic acid, with the chemical formula C10H11NO3, exhibits interesting solubility characteristics that can affect its application in various fields.

Generally, the solubility of this compound can be influenced by several factors:

  • Polarity: Due to the presence of both an acetamide and a carboxylic acid functional group, this compound is polar in nature, which enhances its ability to dissolve in polar solvents such as water.
  • pH Sensitivity: The solubility may vary with the pH of the solution. In acidic environments, the carboxylic acid group may remain protonated, reducing solubility compared to neutral or basic conditions where it can deprotonate and exist as an anion, enhancing solubility.
  • Temperature: The solubility often increases with temperature; thus, higher temperature conditions may facilitate better dissolution.

In conclusion, while 2-(4-acetamidophenyl)acetic acid is generally soluble in water, its solubility profile is context-dependent, influenced by factors such as polarity, pH, and temperature. Understanding these factors is crucial for predicting its behavior in solution and optimizing its use in various applications.

Interesting facts

Interesting Facts About 2-(4-acetamidophenyl)acetic acid

2-(4-acetamidophenyl)acetic acid, also known as paracetamol or acetaminophen in some regions, is a widely used pharmaceutical compound with significant implications in medicine and pharmacology. Here are some intriguing aspects:

  • Pain Management: This compound is well-recognized for its analgesic (pain-relieving) properties, making it a first-line treatment option for moderate pain, including headaches, muscle aches, and arthritis.
  • Antipyretic Effects: Alongside its analgesic capabilities, it also serves as an effective antipyretic, helping to lower fever.
  • Mechanism of Action: Scientists believe that the compound works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins—hormone-like substances that mediate inflammation and pain.
  • Safety Profile: When used appropriately, it is typically well-tolerated; however, exceeding recommended doses can lead to severe liver damage. This highlights the importance of dosage awareness in pharmacology.
  • Wide Accessibility: Due to its effectiveness and relatively low risk of side effects when taken as directed, it is available over the counter in various forms, including tablets, liquids, and suppositories.

As you explore the world of chemistry and pharmacology, remember that the study of compounds like 2-(4-acetamidophenyl)acetic acid extends beyond simple formulas. Their impact on health and well-being underscores the powerful role chemistry plays in our daily lives. As the famous saying goes, "Science is not only compatible with spirituality; it is a profound source of spirituality." This compound is a testament to this connection!

Synonyms
actarit
18699-02-0
2-(4-acetamidophenyl)acetic acid
4-Acetylaminophenylacetic acid
Benzeneacetic acid, 4-(acetylamino)-
4-Acetamidophenylacetic acid
[4-(acetylamino)phenyl]acetic acid
(p-Acetamidophenyl)acetic acid
Actaritum
Orcl
Actarit [INN:JAN]
Actaritum [INN-Latin]
Mirabegron (m9)
MS-932
Actrarit
CCRIS 3777
4-N-Acetylaminophenylacetic acid
4-(Acetylamino)benzeneacetic acid
EINECS 242-511-3
MFCD00196165
MS 932
NSC 170317
NSC-170317
BRN 1640927
HW5B6351RZ
DTXSID0020020
YM-340790
ACTARIT [INN]
ACTARIT [JAN]
ACTARIT [MI]
ACTARIT [MART.]
ACTARIT [WHO-DD]
DTXCID2020
2-14-00-00281 (Beilstein Handbook Reference)
4-Acetylaminophenylacetic acid;MS-932
NCGC00160450-01
Actaritum (INN-Latin)
Mover
ACTARIT (MART.)
SMR000466341
CAS-18699-02-0
UNII-HW5B6351RZ
Orcl (TN)
Actarit (JAN/INN)
Mirabegron metabolite M9
SCHEMBL78305
MLS000759453
MLS000881203
MLS001423954
(4-acetamido-phenyl)acetic acid
CHEMBL1885632
CHEBI:31173
(4-acetamino-phenyl)-acetic acid
HMS2051C06
HMS2235A24
HMS3393C06
HMS3715F18
Acetic acid, (p-acetamidophenyl)-
(4-acetylamino-phenyl)-acetic acid
BCP12510
CS-M1344
PXB99998
Tox21_111820
Tox21_301197
AB6003
NSC170317
s5039
AKOS000104755
Tox21_111820_1
AC-1285
CCG-100840
KS-5131
NC00090
NCGC00160450-02
NCGC00160450-03
NCGC00255094-01
HY-76938
SY067181
DB-044623
NS00026113
Acetic acid, (p-acetamidophenyl)-(6CI,8CI)
EN300-13165
VU0254342-5
D01395
AB00172855-09
AB00172855-11
AB00172855_13
Q4676759
BRD-K33483813-001-10-0
Z90122510
F9995-0122